Kupershmidt S - Search Results

1

HERG is protected from pharmacological block by alpha-1,2-glucosyltransferase function.

Nakajima T, Hayashi K, Viswanathan PC, Kim MY, Anghelescu M, Barksdale KA, Shuai W, Balser JR, Kupershmidt S. Nakajima T, et al. Among authors: kupershmidt s. J Biol Chem. 2007 Feb 23;282(8):5506-13. doi: 10.1074/jbc.M605976200. Epub 2006 Dec 21. J Biol Chem. 2007. PMID: 17189275 Free article.

2

Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator.

Potet F, Petersen CI, Boutaud O, Shuai W, Stepanovic SZ, Balser JR, Kupershmidt S. Potet F, et al. Among authors: kupershmidt s. J Mol Cell Cardiol. 2009 Feb;46(2):257-67. doi: 10.1016/j.yjmcc.2008.10.015. Epub 2008 Nov 5. J Mol Cell Cardiol. 2009. PMID: 19038263 Free PMC article.

3

Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin.

Potet F, Chagot B, Anghelescu M, Viswanathan PC, Stepanovic SZ, Kupershmidt S, Chazin WJ, Balser JR. Potet F, et al. Among authors: kupershmidt s. J Biol Chem. 2009 Mar 27;284(13):8846-54. doi: 10.1074/jbc.M806871200. Epub 2009 Jan 26. J Biol Chem. 2009. PMID: 19171938 Free PMC article.

4

Trafficking-competent KCNQ1 variably influences the function of HERG long QT alleles.

Hayashi K, Shuai W, Sakamoto Y, Higashida H, Yamagishi M, Kupershmidt S. Hayashi K, et al. Among authors: kupershmidt s. Heart Rhythm. 2010 Jul;7(7):973-80. doi: 10.1016/j.hrthm.2010.03.038. Epub 2010 Mar 27. Heart Rhythm. 2010. PMID: 20348026 Free PMC article.

5

Identification and characterization of a compound that protects cardiac tissue from human Ether-à-go-go-related gene (hERG)-related drug-induced arrhythmias.

Potet F, Lorinc AN, Chaigne S, Hopkins CR, Venkataraman R, Stepanovic SZ, Lewis LM, Days E, Sidorov VY, Engers DW, Zou B, Afshartous D, George AL Jr, Campbell CM, Balser JR, Li M, Baudenbacher FJ, Lindsley CW, Weaver CD, Kupershmidt S. Potet F, et al. Among authors: kupershmidt s. J Biol Chem. 2012 Nov 16;287(47):39613-25. doi: 10.1074/jbc.M112.380162. Epub 2012 Oct 2. J Biol Chem. 2012. PMID: 23033485 Free PMC article.

6

Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system.

Kupershmidt S, Yang IC, Sutherland M, Wells KS, Yang T, Yang P, Balser JR, Roden DM. Kupershmidt S, et al. Cardiovasc Res. 2002 Oct;56(1):93-103. doi: 10.1016/s0008-6363(02)00498-4. Cardiovasc Res. 2002. PMID: 12237170

7

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.

Kupershmidt S, Yang IC, Hayashi K, Wei J, Chanthaphaychith S, Petersen CI, Johns DC, George AL Jr, Roden DM, Balser JR. Kupershmidt S, et al. FASEB J. 2003 Dec;17(15):2263-5. doi: 10.1096/fj.02-1057fje. Epub 2003 Oct 2. FASEB J. 2003. PMID: 14525949

8

The evolutionarily conserved residue A653 plays a key role in HERG channel closing.

Stepanovic SZ, Potet F, Petersen CI, Smith JA, Meiler J, Balser JR, Kupershmidt S. Stepanovic SZ, et al. Among authors: kupershmidt s. J Physiol. 2009 Jun 1;587(Pt 11):2555-66. doi: 10.1113/jphysiol.2008.166694. Epub 2009 Apr 30. J Physiol. 2009. PMID: 19406877 Free PMC article.

9

A calcium sensor in the sodium channel modulates cardiac excitability.

Tan HL, Kupershmidt S, Zhang R, Stepanovic S, Roden DM, Wilde AA, Anderson ME, Balser JR. Tan HL, et al. Among authors: kupershmidt s. Nature. 2002 Jan 24;415(6870):442-7. doi: 10.1038/415442a. Nature. 2002. PMID: 11807557

10

Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channels.

Fukuda K, Davies SS, Nakajima T, Ong BH, Kupershmidt S, Fessel J, Amarnath V, Anderson ME, Boyden PA, Viswanathan PC, Roberts LJ 2nd, Balser JR. Fukuda K, et al. Among authors: kupershmidt s. Circ Res. 2005 Dec 9;97(12):1262-9. doi: 10.1161/01.RES.0000195844.31466.e9. Epub 2005 Nov 10. Circ Res. 2005. PMID: 16284182

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