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The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape.
Loffredo JT, Burwitz BJ, Rakasz EG, Spencer SP, Stephany JJ, Vela JP, Martin SR, Reed J, Piaskowski SM, Furlott J, Weisgrau KL, Rodrigues DS, Soma T, Napoé G, Friedrich TC, Wilson NA, Kallas EG, Watkins DI. Loffredo JT, et al. Among authors: stephany jj. J Virol. 2007 Mar;81(6):2624-34. doi: 10.1128/JVI.01912-06. Epub 2006 Dec 27. J Virol. 2007. PMID: 17192314 Free PMC article.
Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression.
Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, Bean AT, Lee W, Burwitz BJ, Stephany JJ, Loffredo JT, Allison DB, Adnan S, Hoji A, Wilson NA, Friedrich TC, Lifson JD, Yang OO, Watkins DI. Sacha JB, et al. Among authors: stephany jj. J Immunol. 2007 Mar 1;178(5):2746-54. doi: 10.4049/jimmunol.178.5.2746. J Immunol. 2007. PMID: 17312117 Free PMC article.
CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.
Loffredo JT, Friedrich TC, León EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. Loffredo JT, et al. Among authors: stephany jj. PLoS One. 2007 Nov 14;2(11):e1152. doi: 10.1371/journal.pone.0001152. PLoS One. 2007. PMID: 18000532 Free PMC article.
Consequences of cytotoxic T-lymphocyte escape: common escape mutations in simian immunodeficiency virus are poorly recognized in naive hosts.
Friedrich TC, McDermott AB, Reynolds MR, Piaskowski S, Fuenger S, De Souza IP, Rudersdorf R, Cullen C, Yant LJ, Vojnov L, Stephany J, Martin S, O'Connor DH, Wilson N, Watkins DI. Friedrich TC, et al. J Virol. 2004 Sep;78(18):10064-73. doi: 10.1128/JVI.78.18.10064-10073.2004. J Virol. 2004. PMID: 15331739 Free PMC article.
Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics.
Rose JC, Stephany JJ, Valente WJ, Trevillian BM, Dang HV, Bielas JH, Maly DJ, Fowler DM. Rose JC, et al. Among authors: stephany jj. Nat Methods. 2017 Sep;14(9):891-896. doi: 10.1038/nmeth.4368. Epub 2017 Jul 24. Nat Methods. 2017. PMID: 28737741 Free PMC article.
23 results