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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis.
Ma F, Plazyo O, Billi AC, Tsoi LC, Xing X, Wasikowski R, Gharaee-Kermani M, Hile G, Jiang Y, Harms PW, Xing E, Kirma J, Xi J, Hsu JE, Sarkar MK, Chung Y, Di Domizio J, Gilliet M, Ward NL, Maverakis E, Klechevsky E, Voorhees JJ, Elder JT, Lee JH, Kahlenberg JM, Pellegrini M, Modlin RL, Gudjonsson JE. Ma F, et al. Among authors: gilliet m. Nat Commun. 2023 Jun 12;14(1):3455. doi: 10.1038/s41467-023-39020-4. Nat Commun. 2023. PMID: 37308489 Free PMC article.
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.
Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B, Gilliet M, Ho S, Antonenko S, Lauerma A, Smith K, Gorman D, Zurawski S, Abrams J, Menon S, McClanahan T, de Waal-Malefyt Rd R, Bazan F, Kastelein RA, Liu YJ. Soumelis V, et al. Among authors: gilliet m. Nat Immunol. 2002 Jul;3(7):673-80. doi: 10.1038/ni805. Epub 2002 Jun 10. Nat Immunol. 2002. PMID: 12055625
146 results