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Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass.
Ristow M, Mulder H, Pomplun D, Schulz TJ, Müller-Schmehl K, Krause A, Fex M, Puccio H, Müller J, Isken F, Spranger J, Müller-Wieland D, Magnuson MA, Möhlig M, Koenig M, Pfeiffer AF. Ristow M, et al. J Clin Invest. 2003 Aug;112(4):527-34. doi: 10.1172/JCI18107. J Clin Invest. 2003. PMID: 12925693 Free PMC article.
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice.
Thierbach R, Schulz TJ, Isken F, Voigt A, Mietzner B, Drewes G, von Kleist-Retzow JC, Wiesner RJ, Magnuson MA, Puccio H, Pfeiffer AF, Steinberg P, Ristow M. Thierbach R, et al. Among authors: ristow m. Hum Mol Genet. 2005 Dec 15;14(24):3857-64. doi: 10.1093/hmg/ddi410. Epub 2005 Nov 8. Hum Mol Genet. 2005. PMID: 16278235
Improved glucose metabolism in mice lacking alpha-tocopherol transfer protein.
Birringer M, Kuhlow D, Pfluger PT, Landes N, Schulz TJ, Glaubitz M, Florian S, Pfeiffer A, Schuelke M, Brigelius-Flohé R, Ristow M. Birringer M, et al. Among authors: ristow m. Eur J Nutr. 2007 Oct;46(7):397-405. doi: 10.1007/s00394-007-0679-2. Epub 2007 Sep 19. Eur J Nutr. 2007. PMID: 17882348
158 results