Brocchini S - Search Results

1

Site-specific PEGylation of protein disulfide bonds using a three-carbon bridge.

Balan S, Choi JW, Godwin A, Teo I, Laborde CM, Heidelberger S, Zloh M, Shaunak S, Brocchini S. Balan S, et al. Among authors: brocchini s. Bioconjug Chem. 2007 Jan-Feb;18(1):61-76. doi: 10.1021/bc0601471. Bioconjug Chem. 2007. PMID: 17226958

2

Narrow Molecular Weight Distribution Precursors for Polymer-Drug Conjugates We are grateful for funding from the EPSRC and the School of Pharmacy (A.G.) and Mr. Derek Marley for conducting the atomic absorption analysis.

Godwin A, Hartenstein M, Müller AH, Brocchini S. Godwin A, et al. Among authors: brocchini s. Angew Chem Int Ed Engl. 2001 Feb 2;40(3):594-597. Angew Chem Int Ed Engl. 2001. PMID: 11180382 No abstract available.

3

N-(2-hydroxypropyl)methacrylamide copolymer-6-(3-aminopropyl)-ellipticine conjugates. Synthesis, in vitro, and preliminary in vivo evaluation.

Searle F, Gac-Breton S, Keane R, Dimitrijevic S, Brocchini S, Sausville EA, Duncan R. Searle F, et al. Among authors: brocchini s. Bioconjug Chem. 2001 Sep-Oct;12(5):711-8. doi: 10.1021/bc0001544. Bioconjug Chem. 2001. PMID: 11562189

4

New strategies for polymer development in pharmaceutical science--a short review.

Godwin A, Bolina K, Clochard M, Dinand E, Rankin S, Simic S, Brocchini S. Godwin A, et al. Among authors: brocchini s. J Pharm Pharmacol. 2001 Sep;53(9):1175-84. doi: 10.1211/0022357011776612. J Pharm Pharmacol. 2001. PMID: 11578099 Review.

5

Polyacetal-doxorubicin conjugates designed for pH-dependent degradation.

Tomlinson R, Heller J, Brocchini S, Duncan R. Tomlinson R, et al. Among authors: brocchini s. Bioconjug Chem. 2003 Nov-Dec;14(6):1096-106. doi: 10.1021/bc030028a. Bioconjug Chem. 2003. PMID: 14624622

6

Polyvalent dendrimer glucosamine conjugates prevent scar tissue formation.

Shaunak S, Thomas S, Gianasi E, Godwin A, Jones E, Teo I, Mireskandari K, Luthert P, Duncan R, Patterson S, Khaw P, Brocchini S. Shaunak S, et al. Among authors: brocchini s. Nat Biotechnol. 2004 Aug;22(8):977-84. doi: 10.1038/nbt995. Epub 2004 Jul 18. Nat Biotechnol. 2004. PMID: 15258595

7

Site-specific PEGylation of native disulfide bonds in therapeutic proteins.

Shaunak S, Godwin A, Choi JW, Balan S, Pedone E, Vijayarangam D, Heidelberger S, Teo I, Zloh M, Brocchini S. Shaunak S, et al. Among authors: brocchini s. Nat Chem Biol. 2006 Jun;2(6):312-3. doi: 10.1038/nchembio786. Epub 2006 Apr 23. Nat Chem Biol. 2006. PMID: 16633351

8

PEGylation of native disulfide bonds in proteins.

Brocchini S, Balan S, Godwin A, Choi JW, Zloh M, Shaunak S. Brocchini S, et al. Nat Protoc. 2006;1(5):2241-52. doi: 10.1038/nprot.2006.346. Nat Protoc. 2006. PMID: 17406463

9

Identification and insertion of 3-carbon bridges in protein disulfide bonds: a computational approach.

Zloh M, Shaunak S, Balan S, Brocchini S. Zloh M, et al. Among authors: brocchini s. Nat Protoc. 2007;2(5):1070-83. doi: 10.1038/nprot.2007.119. Nat Protoc. 2007. PMID: 17545999

10

Disulfide bridge based PEGylation of proteins.

Brocchini S, Godwin A, Balan S, Choi JW, Zloh M, Shaunak S. Brocchini S, et al. Adv Drug Deliv Rev. 2008 Jan 3;60(1):3-12. doi: 10.1016/j.addr.2007.06.014. Epub 2007 Aug 17. Adv Drug Deliv Rev. 2008. PMID: 17920720 Review.

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