Smithson L - Search Results

1

Abeta40 inhibits amyloid deposition in vivo.

Kim J, Onstead L, Randle S, Price R, Smithson L, Zwizinski C, Dickson DW, Golde T, McGowan E. Kim J, et al. Among authors: smithson l. J Neurosci. 2007 Jan 17;27(3):627-33. doi: 10.1523/JNEUROSCI.4849-06.2007. J Neurosci. 2007. PMID: 17234594 Free PMC article.

2

BRI2 (ITM2b) inhibits Abeta deposition in vivo.

Kim J, Miller VM, Levites Y, West KJ, Zwizinski CW, Moore BD, Troendle FJ, Bann M, Verbeeck C, Price RW, Smithson L, Sonoda L, Wagg K, Rangachari V, Zou F, Younkin SG, Graff-Radford N, Dickson D, Rosenberry T, Golde TE. Kim J, et al. Among authors: smithson l. J Neurosci. 2008 Jun 4;28(23):6030-6. doi: 10.1523/JNEUROSCI.0891-08.2008. J Neurosci. 2008. PMID: 18524908 Free PMC article.

3

Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models.

Levites Y, Smithson LA, Price RW, Dakin RS, Yuan B, Sierks MR, Kim J, McGowan E, Reed DK, Rosenberry TL, Das P, Golde TE. Levites Y, et al. Among authors: smithson la. FASEB J. 2006 Dec;20(14):2576-8. doi: 10.1096/fj.06-6463fje. Epub 2006 Oct 26. FASEB J. 2006. PMID: 17068112

4

Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.

Levites Y, Jansen K, Smithson LA, Dakin R, Holloway VM, Das P, Golde TE. Levites Y, et al. J Neurosci. 2006 Nov 15;26(46):11923-8. doi: 10.1523/JNEUROSCI.2795-06.2006. J Neurosci. 2006. PMID: 17108166 Free PMC article.

5

Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy.

Das P, Smithson LA, Price RW, Holloway VM, Levites Y, Chakrabarty P, Golde TE. Das P, et al. J Neuroinflammation. 2006 Jul 26;3:17. doi: 10.1186/1742-2094-3-17. J Neuroinflammation. 2006. PMID: 16872492 Free PMC article.

6

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM. Price AR, et al. Science. 2013 May 24;340(6135):924-d. doi: 10.1126/science.1234089. Science. 2013. PMID: 23704553

7

The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activity.

Park HJ, Ran Y, Jung JI, Holmes O, Price AR, Smithson L, Ceballos-Diaz C, Han C, Wolfe MS, Daaka Y, Ryabinin AE, Kim SH, Hauger RL, Golde TE, Felsenstein KM. Park HJ, et al. Among authors: smithson l. EMBO J. 2015 Jun 12;34(12):1674-86. doi: 10.15252/embj.201488795. Epub 2015 May 11. EMBO J. 2015. PMID: 25964433 Free PMC article.

8

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.

Jung JI, Price AR, Ladd TB, Ran Y, Park HJ, Ceballos-Diaz C, Smithson LA, Hochhaus G, Tang Y, Akula R, Ba S, Koo EH, Shapiro G, Felsenstein KM, Golde TE. Jung JI, et al. Mol Neurodegener. 2015 Jul 14;10:29. doi: 10.1186/s13024-015-0021-z. Mol Neurodegener. 2015. PMID: 26169917 Free PMC article.

9

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Abeta levels.

Lawlor PA, Bland RJ, Das P, Price RW, Holloway V, Smithson L, Dicker BL, During MJ, Young D, Golde TE. Lawlor PA, et al. Among authors: smithson l. Mol Neurodegener. 2007 Jun 9;2:11. doi: 10.1186/1750-1326-2-11. Mol Neurodegener. 2007. PMID: 17559680 Free PMC article.

10

Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.

Li T, Wen H, Brayton C, Das P, Smithson LA, Fauq A, Fan X, Crain BJ, Price DL, Golde TE, Eberhart CG, Wong PC. Li T, et al. Among authors: smithson la. J Biol Chem. 2007 Nov 2;282(44):32264-73. doi: 10.1074/jbc.M703649200. Epub 2007 Sep 7. J Biol Chem. 2007. PMID: 17827153 Free article.

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