Ju J - Search Results

1

Single chemical modifications of the C-1027 enediyne core, a radiomimetic antitumor drug, affect both drug potency and the role of ataxia-telangiectasia mutated in cellular responses to DNA double-strand breaks.

Kennedy DR, Gawron LS, Ju J, Liu W, Shen B, Beerman TA. Kennedy DR, et al. Among authors: ju j. Cancer Res. 2007 Jan 15;67(2):773-81. doi: 10.1158/0008-5472.CAN-06-2893. Cancer Res. 2007. PMID: 17234789

2

Conversion of (2S)-arginine to (2S,3R)-capreomycidine by VioC and VioD from the viomycin biosynthetic pathway of Streptomyces sp. strain ATCC11861.

Ju J, Ozanick SG, Shen B, Thomas MG. Ju J, et al. Chembiochem. 2004 Sep 6;5(9):1281-5. doi: 10.1002/cbic.200400136. Chembiochem. 2004. PMID: 15368582 No abstract available.

3

Antitumor antibiotics: bleomycin, enediynes, and mitomycin.

Galm U, Hager MH, Van Lanen SG, Ju J, Thorson JS, Shen B. Galm U, et al. Among authors: ju j. Chem Rev. 2005 Feb;105(2):739-58. doi: 10.1021/cr030117g. Chem Rev. 2005. PMID: 15700963 No abstract available.

4

Migrastatin and dorrigocins are shunt metabolites of iso-migrastatin.

Ju J, Lim SK, Jiang H, Shen B. Ju J, et al. J Am Chem Soc. 2005 Feb 16;127(6):1622-3. doi: 10.1021/ja043808i. J Am Chem Soc. 2005. PMID: 15700980

5

Biosynthesis of the beta-amino acid moiety of the enediyne antitumor antibiotic C-1027 featuring beta-amino acyl-S-carrier protein intermediates.

Van Lanen SG, Dorrestein PC, Christenson SD, Liu W, Ju J, Kelleher NL, Shen B. Van Lanen SG, et al. Among authors: ju j. J Am Chem Soc. 2005 Aug 24;127(33):11594-5. doi: 10.1021/ja052871k. J Am Chem Soc. 2005. PMID: 16104723

6

Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.

Ju J, Lim SK, Jiang H, Seo JW, Shen B. Ju J, et al. J Am Chem Soc. 2005 Aug 31;127(34):11930-1. doi: 10.1021/ja053118u. J Am Chem Soc. 2005. PMID: 16117518

7

Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.

Li W, Ju J, Osada H, Shen B. Li W, et al. Among authors: ju j. J Bacteriol. 2006 Jun;188(11):4148-52. doi: 10.1128/JB.00172-06. J Bacteriol. 2006. PMID: 16707708 Free PMC article.

8

Thermolysis of isomigrastatin and its congeners via [3,3]-sigmatropic rearrangement: a new route to the synthesis of migrastatin and its analogues.

Ju J, Lim SK, Jiang H, Seo JW, Her Y, Shen B. Ju J, et al. Org Lett. 2006 Dec 7;8(25):5865-8. doi: 10.1021/ol062470p. Org Lett. 2006. PMID: 17134292 Free PMC article.

9

Signal mimics derived from a metagenomic analysis of the gypsy moth gut microbiota.

Guan C, Ju J, Borlee BR, Williamson LL, Shen B, Raffa KF, Handelsman J. Guan C, et al. Among authors: ju j. Appl Environ Microbiol. 2007 Jun;73(11):3669-76. doi: 10.1128/AEM.02617-06. Epub 2007 Apr 13. Appl Environ Microbiol. 2007. PMID: 17435000 Free PMC article.

10

Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses.

Kennedy DR, Ju J, Shen B, Beerman TA. Kennedy DR, et al. Among authors: ju j. Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17632-7. doi: 10.1073/pnas.0708274104. Epub 2007 Oct 31. Proc Natl Acad Sci U S A. 2007. PMID: 17978180 Free PMC article.

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