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D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
Juang SH, Lung CC, Hsu PC, Hsu KS, Li YC, Hong PC, Shiah HS, Kuo CC, Huang CW, Wang YC, Huang L, Chen TS, Chen SF, Fu KC, Hsu CL, Lin MJ, Chang CJ, Ashendel CL, Chan TC, Chou KM, Chang JY. Juang SH, et al. Among authors: hsu pc, hsu ks, hsu cl. Mol Cancer Ther. 2007 Jan;6(1):193-202. doi: 10.1158/1535-7163.MCT-06-0482. Mol Cancer Ther. 2007. PMID: 17237279
216 results