Phan LT - Search Results

1

EDP-420, a bicyclolide (bridged bicyclic macrolide), is active against Mycobacterium avium.

Bermudez LE, Motamedi N, Chee C, Baimukanova G, Kolonoski P, Inderlied C, Aralar P, Wang G, Phan LT, Young LS. Bermudez LE, et al. Among authors: phan lt. Antimicrob Agents Chemother. 2007 May;51(5):1666-70. doi: 10.1128/AAC.01303-06. Epub 2007 Feb 12. Antimicrob Agents Chemother. 2007. PMID: 17296742 Free PMC article.

2

The efficacy of clarithromycin and the bicyclolide EDP-420 against Mycobacterium avium in a mouse model of pulmonary infection.

Bermudez LE, Motamedi N, Kolonoski P, Chee C, Baimukanova G, Bildfell R, Wang G, Phan LT, Lowell SY. Bermudez LE, et al. Among authors: phan lt. J Infect Dis. 2008 Jun 1;197(11):1506-10. doi: 10.1086/587906. J Infect Dis. 2008. PMID: 18422455

3

Effects of EDP-420 on penicillin-resistant and quinolone- and penicillin-resistant pneumococci in the rabbit meningitis model.

Stucki A, Gerber P, Acosta F, Cottagnoud M, Cottagnoud P, Jiang L, Nguyen P, Wachtel D, Wang G, Phan LT. Stucki A, et al. Among authors: phan lt. J Antimicrob Chemother. 2008 Mar;61(3):665-9. doi: 10.1093/jac/dkm505. Epub 2008 Jan 25. J Antimicrob Chemother. 2008. PMID: 18222952 Free article.

4

Pharmacodynamic profiling of modithromycin: assessment in a pneumococcal murine pneumonia model.

Maglio D, Sun HK, Patel T, Banevicius MA, Nightingale CH, Arya A, Wang G, Chen Z, Phan LT, Nicolau DP. Maglio D, et al. Among authors: phan lt. Int J Antimicrob Agents. 2014 Jun;43(6):540-6. doi: 10.1016/j.ijantimicag.2014.01.029. Epub 2014 Mar 19. Int J Antimicrob Agents. 2014. PMID: 24703590

5

In vitro activities of the novel bicyclolides modithromycin (EDP-420, EP-013420, S-013420) and EDP-322 against MDR clinical Neisseria gonorrhoeae isolates and international reference strains.

Jacobsson S, Golparian D, Phan LT, Ohnishi M, Fredlund H, Or YS, Unemo M. Jacobsson S, et al. Among authors: phan lt. J Antimicrob Chemother. 2015 Jan;70(1):173-7. doi: 10.1093/jac/dku344. Epub 2014 Sep 1. J Antimicrob Chemother. 2015. PMID: 25182063

6

Synthesis of novel 6,11-O-bridged bicyclic ketolides via a palladium-catalyzed bis-allylation.

Wang G, Niu D, Qiu YL, Phan LT, Chen Z, Polemeropoulos A, Or YS. Wang G, et al. Among authors: phan lt. Org Lett. 2004 Nov 25;6(24):4455-8. doi: 10.1021/ol048336r. Org Lett. 2004. PMID: 15548049

7

Synthesis of new 14-membered macrolide antibiotics via a novel ring contraction metathesis.

Lazarova TI, Binet SM, Vo NH, Chen JS, Phan LT, Or YS. Lazarova TI, et al. Among authors: phan lt. Org Lett. 2003 Feb 20;5(4):443-5. doi: 10.1021/ol027322n. Org Lett. 2003. PMID: 12583739

8

Synthesis of novel 4'-substituted 16-membered ring macrolide antibiotics derived from leucomycins.

Wang Z, Jian T, Phan LT, Or YS. Wang Z, et al. Among authors: phan lt. Bioorg Med Chem Lett. 2004 Jan 19;14(2):519-21. doi: 10.1016/j.bmcl.2003.10.028. Bioorg Med Chem Lett. 2004. PMID: 14698194

9

Synthesis and antibacterial activity of a novel class of 4'-substituted 16-membered ring macrolides derived from tylosin.

Phan LT, Jian T, Chen Z, Qiu YL, Wang Z, Beach T, Polemeropoulos A, Or YS. Phan LT, et al. J Med Chem. 2004 Jun 3;47(12):2965-8. doi: 10.1021/jm034233n. J Med Chem. 2004. PMID: 15163176

10

Synthesis of 2-fluoro-6-O-propargyl-11,12-carbamate ketolides. A novel class of antibiotics.

Phan LT, Clark RF, Rupp M, Or YS, Chu DT, Ma Z. Phan LT, et al. Org Lett. 2000 Sep 21;2(19):2951-4. doi: 10.1021/ol006226o. Org Lett. 2000. PMID: 10986080

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