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Inhibition of IK,ACh current may contribute to clinical efficacy of class I and class III antiarrhythmic drugs in patients with atrial fibrillation.
Voigt N, Rozmaritsa N, Trausch A, Zimniak T, Christ T, Wettwer E, Matschke K, Dobrev D, Ravens U. Voigt N, et al. Among authors: wettwer e. Naunyn Schmiedebergs Arch Pharmacol. 2010 Mar;381(3):251-9. doi: 10.1007/s00210-009-0452-6. Epub 2009 Sep 17. Naunyn Schmiedebergs Arch Pharmacol. 2010. PMID: 19760273 Clinical Trial.
Atrial selectivity of antiarrhythmic drugs.
Ravens U, Poulet C, Wettwer E, Knaut M. Ravens U, et al. Among authors: wettwer e. J Physiol. 2013 Sep 1;591(17):4087-97. doi: 10.1113/jphysiol.2013.256115. Epub 2013 Jun 3. J Physiol. 2013. PMID: 23732646 Free PMC article. Review.
Application of the RIMARC algorithm to a large data set of action potentials and clinical parameters for risk prediction of atrial fibrillation.
Ravens U, Katircioglu-Öztürk D, Wettwer E, Christ T, Dobrev D, Voigt N, Poulet C, Loose S, Simon J, Stein A, Matschke K, Knaut M, Oto E, Oto A, Güvenir HA. Ravens U, et al. Among authors: wettwer e. Med Biol Eng Comput. 2015 Mar;53(3):263-73. doi: 10.1007/s11517-014-1232-0. Epub 2014 Dec 3. Med Biol Eng Comput. 2015. PMID: 25466224 Free article.
Molecular basis of downregulation of G-protein-coupled inward rectifying K(+) current (I(K,ACh) in chronic human atrial fibrillation: decrease in GIRK4 mRNA correlates with reduced I(K,ACh) and muscarinic receptor-mediated shortening of action potentials.
Dobrev D, Graf E, Wettwer E, Himmel HM, Hála O, Doerfel C, Christ T, Schüler S, Ravens U. Dobrev D, et al. Among authors: wettwer e. Circulation. 2001 Nov 20;104(21):2551-7. doi: 10.1161/hc4601.099466. Circulation. 2001. PMID: 11714649
96 results