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Characterization of a cellular protease that cleaves Pseudomonas exotoxin.
Fryling C, Ogata M, FitzGerald D. Fryling C, et al. Among authors: fitzgerald d. Infect Immun. 1992 Feb;60(2):497-502. doi: 10.1128/iai.60.2.497-502.1992. Infect Immun. 1992. PMID: 1730481 Free PMC article.
Pseudomonas exotoxin (PE) is a 66-kDa bacterial toxin that is proteolytically cleaved by cells to produce an N-terminal fragment of 28 kDa and a C-terminal 37-kDa fragment which translocates to the cytosol and inhibits protein synthesis (M. Ogata, V.K. Chaudhary, I. Pastan, and …
Pseudomonas exotoxin (PE) is a 66-kDa bacterial toxin that is proteolytically cleaved by cells to produce an N-terminal fragment of 28 kDa a …
Comparative immunogenicity of conjugates composed of the Staphylococcus aureus type 8 capsular polysaccharide bound to carrier proteins by adipic acid dihydrazide or N-succinimidyl-3-(2-pyridyldithio)propionate.
Fattom A, Shiloach J, Bryla D, Fitzgerald D, Pastan I, Karakawa WW, Robbins JB, Schneerson R. Fattom A, et al. Among authors: fitzgerald d. Infect Immun. 1992 Feb;60(2):584-9. doi: 10.1128/iai.60.2.584-589.1992. Infect Immun. 1992. PMID: 1730492 Free PMC article.
Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.
Seetharam S, Chaudhary VK, FitzGerald D, Pastan I. Seetharam S, et al. Among authors: fitzgerald d. J Biol Chem. 1991 Sep 15;266(26):17376-81. J Biol Chem. 1991. PMID: 1910044 Free article.
The sequence Arg-Glu-Asp-Leu-Lys (REDLK) at the carboxyl terminus of Pseudomonas exotoxin has been shown to be important for its cytotoxic activity (Chaudhary, V. K., Jinno, Y., FitzGerald, D. J., and Pastan, I. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 308-312). In …
The sequence Arg-Glu-Asp-Leu-Lys (REDLK) at the carboxyl terminus of Pseudomonas exotoxin has been shown to be important for its cytotoxic a …
Redirecting Pseudomonas exotoxin.
FitzGerald D, Pastan I. FitzGerald D, et al. Semin Cell Biol. 1991 Feb;2(1):31-7. Semin Cell Biol. 1991. PMID: 1954341 Review.
1,824 results