Whetstone H - Search Results

1

PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms.

Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA. Mau E, et al. Among authors: whetstone h. Dev Biol. 2007 May 1;305(1):28-39. doi: 10.1016/j.ydbio.2007.01.031. Epub 2007 Jan 27. Dev Biol. 2007. PMID: 17328886 Free article.

2

Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.

Ho L, Stojanovski A, Whetstone H, Wei QX, Mau E, Wunder JS, Alman B. Ho L, et al. Among authors: whetstone h. Cancer Cell. 2009 Aug 4;16(2):126-36. doi: 10.1016/j.ccr.2009.05.013. Cancer Cell. 2009. PMID: 19647223 Free article.

3

Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation.

Chen Y, Whetstone HC, Youn A, Nadesan P, Chow EC, Lin AC, Alman BA. Chen Y, et al. J Biol Chem. 2007 Jan 5;282(1):526-33. doi: 10.1074/jbc.M602700200. Epub 2006 Nov 3. J Biol Chem. 2007. PMID: 17085452 Free article.

4

Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.

Chen Y, Whetstone HC, Lin AC, Nadesan P, Wei Q, Poon R, Alman BA. Chen Y, et al. PLoS Med. 2007 Jul 31;4(7):e249. doi: 10.1371/journal.pmed.0040249. PLoS Med. 2007. PMID: 17676991 Free PMC article.

5

Beta-catenin regulates wound size and mediates the effect of TGF-beta in cutaneous healing.

Cheon SS, Wei Q, Gurung A, Youn A, Bright T, Poon R, Whetstone H, Guha A, Alman BA. Cheon SS, et al. Among authors: whetstone h. FASEB J. 2006 Apr;20(6):692-701. doi: 10.1096/fj.05-4759com. FASEB J. 2006. PMID: 16581977

6

Modulating hedgehog signaling can attenuate the severity of osteoarthritis.

Lin AC, Seeto BL, Bartoszko JM, Khoury MA, Whetstone H, Ho L, Hsu C, Ali SA, Alman BA. Lin AC, et al. Among authors: whetstone h. Nat Med. 2009 Dec;15(12):1421-5. doi: 10.1038/nm.2055. Epub 2009 Nov 15. Nat Med. 2009. PMID: 19915594

7

Fibronectin and beta-catenin act in a regulatory loop in dermal fibroblasts to modulate cutaneous healing.

Bielefeld KA, Amini-Nik S, Whetstone H, Poon R, Youn A, Wang J, Alman BA. Bielefeld KA, et al. Among authors: whetstone h. J Biol Chem. 2011 Aug 5;286(31):27687-97. doi: 10.1074/jbc.M111.261677. Epub 2011 Jun 7. J Biol Chem. 2011. PMID: 21652705 Free PMC article.

8

Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas.

Wang CY, Wei Q, Han I, Sato S, Ghanbari-Azarnier R, Whetstone H, Poon R, Hu J, Zheng F, Zhang P, Wang W, Wunder JS, Alman BA. Wang CY, et al. Among authors: whetstone h. Cancer Res. 2012 Feb 15;72(4):1013-22. doi: 10.1158/0008-5472.CAN-11-2531. Epub 2012 Jan 9. Cancer Res. 2012. PMID: 22232736

9

Activation of hedgehog signaling during fracture repair enhances osteoblastic-dependent matrix formation.

Baht GS, Silkstone D, Nadesan P, Whetstone H, Alman BA. Baht GS, et al. Among authors: whetstone h. J Orthop Res. 2014 Apr;32(4):581-6. doi: 10.1002/jor.22562. Epub 2013 Dec 17. J Orthop Res. 2014. PMID: 24347536 Free article.

10

Hedgehog pathway inhibition in chondrosarcoma using the smoothened inhibitor IPI-926 directly inhibits sarcoma cell growth.

Campbell VT, Nadesan P, Ali SA, Wang CY, Whetstone H, Poon R, Wei Q, Keilty J, Proctor J, Wang LW, Apte SS, McGovern K, Alman BA, Wunder JS. Campbell VT, et al. Among authors: whetstone h. Mol Cancer Ther. 2014 May;13(5):1259-69. doi: 10.1158/1535-7163.MCT-13-0731. Epub 2014 Mar 14. Mol Cancer Ther. 2014. PMID: 24634412

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