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Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction.
Dierssen M, Gratacòs M, Sahún I, Martín M, Gallego X, Amador-Arjona A, Martínez de Lagrán M, Murtra P, Martí E, Pujana MA, Ferrer I, Dalfó E, Martínez-Cué C, Flórez J, Torres-Peraza JF, Alberch J, Maldonado R, Fillat C, Estivill X. Dierssen M, et al. Neurobiol Dis. 2006 Nov;24(2):403-18. doi: 10.1016/j.nbd.2006.07.015. Epub 2006 Sep 11. Neurobiol Dis. 2006. PMID: 16963267
A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.
Pereira PL, Magnol L, Sahún I, Brault V, Duchon A, Prandini P, Gruart A, Bizot JC, Chadefaux-Vekemans B, Deutsch S, Trovero F, Delgado-García JM, Antonarakis SE, Dierssen M, Herault Y. Pereira PL, et al. Among authors: dierssen m. Hum Mol Genet. 2009 Dec 15;18(24):4756-69. doi: 10.1093/hmg/ddp438. Epub 2009 Sep 26. Hum Mol Genet. 2009. PMID: 19783846 Free PMC article.
Increased opioid dependence in a mouse model of panic disorder.
Gallego X, Murtra P, Zamalloa T, Canals JM, Pineda J, Amador-Arjona A, Maldonado R, Dierssen M. Gallego X, et al. Among authors: dierssen m. Front Behav Neurosci. 2010 Feb 22;3:60. doi: 10.3389/neuro.08.060.2009. eCollection 2010. Front Behav Neurosci. 2010. PMID: 20204153 Free PMC article.
Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.
Teixeira CM, Martín ED, Sahún I, Masachs N, Pujadas L, Corvelo A, Bosch C, Rossi D, Martinez A, Maldonado R, Dierssen M, Soriano E. Teixeira CM, et al. Among authors: dierssen m. Neuropsychopharmacology. 2011 Nov;36(12):2395-405. doi: 10.1038/npp.2011.153. Epub 2011 Aug 3. Neuropsychopharmacology. 2011. PMID: 21814183 Free PMC article.
Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M. Gallego X, et al. Among authors: dierssen m. Amino Acids. 2012 Aug;43(2):897-909. doi: 10.1007/s00726-011-1149-y. Epub 2011 Nov 19. Amino Acids. 2012. PMID: 22101982
Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice.
Dierssen M, Fedrizzi L, Gomez-Villafuertes R, de Lagran MM, Gutierrez-Adan A, Sahún I, Pintado B, Oliveros JC, Dopazo XM, Gonzalez P, Brini M, Mellström B, Carafoli E, Naranjo JR. Dierssen M, et al. Front Mol Neurosci. 2012 May 3;5:58. doi: 10.3389/fnmol.2012.00058. eCollection 2012. Front Mol Neurosci. 2012. PMID: 22563308 Free PMC article.
231 results