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C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A.
Lamberti A, Longo O, Marra M, Tagliaferri P, Bismuto E, Fiengo A, Viscomi C, Budillon A, Rapp UR, Wang E, Venuta S, Abbruzzese A, Arcari P, Caraglia M. Lamberti A, et al. Among authors: marra m. Cell Death Differ. 2007 May;14(5):952-62. doi: 10.1038/sj.cdd.4402102. Epub 2007 Mar 2. Cell Death Differ. 2007. PMID: 17332776
The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
Caraglia M, Marra M, Viscomi C, D'Alessandro AM, Budillon A, Meo G, Arra C, Barbieri A, Rapp UR, Baldi A, Tassone P, Venuta S, Abbruzzese A, Tagliaferri P. Caraglia M, et al. Among authors: marra m. Int J Cancer. 2007 Nov 15;121(10):2317-30. doi: 10.1002/ijc.22964. Int J Cancer. 2007. PMID: 17657738
Raf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells.
Sanges C, Scheuermann C, Zahedi RP, Sickmann A, Lamberti A, Migliaccio N, Baljuls A, Marra M, Zappavigna S, Reinders J, Rapp U, Abbruzzese A, Caraglia M, Arcari P. Sanges C, et al. Among authors: marra m. Cell Death Dis. 2012 Mar 1;3(3):e276. doi: 10.1038/cddis.2012.16. Cell Death Dis. 2012. PMID: 22378069 Free PMC article.
The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.
Caraglia M, D'Alessandro AM, Marra M, Giuberti G, Vitale G, Viscomi C, Colao A, Prete SD, Tagliaferri P, Tassone P, Budillon A, Venuta S, Abbruzzese A. Caraglia M, et al. Among authors: marra m. Oncogene. 2004 Sep 9;23(41):6900-13. doi: 10.1038/sj.onc.1207814. Oncogene. 2004. PMID: 15286715
Alpha-interferon and its effects on signal transduction pathways.
Caraglia M, Marra M, Pelaia G, Maselli R, Caputi M, Marsico SA, Abbruzzese A. Caraglia M, et al. Among authors: marra m. J Cell Physiol. 2005 Feb;202(2):323-35. doi: 10.1002/jcp.20137. J Cell Physiol. 2005. PMID: 15389589 Review.
1,243 results