Keith KA - Search Results

1

N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors.

Bailey TR, Rippin SR, Opsitnick E, Burns CJ, Pevear DC, Collett MS, Rhodes G, Tohan S, Huggins JW, Baker RO, Kern ER, Keith KA, Dai D, Yang G, Hruby D, Jordan R. Bailey TR, et al. Among authors: keith ka. J Med Chem. 2007 Apr 5;50(7):1442-4. doi: 10.1021/jm061484y. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335190 Free PMC article.

2

Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents.

Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER. Pirrung MC, et al. Among authors: keith ka. J Med Chem. 2005 Apr 21;48(8):3045-50. doi: 10.1021/jm049147h. J Med Chem. 2005. PMID: 15828843

3

Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses.

Beadle JR, Wan WB, Ciesla SL, Keith KA, Hartline C, Kern ER, Hostetler KY. Beadle JR, et al. Among authors: keith ka. J Med Chem. 2006 Mar 23;49(6):2010-5. doi: 10.1021/jm050473m. J Med Chem. 2006. PMID: 16539388

4

A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity.

Fan X, Zhang X, Zhou L, Keith KA, Kern ER, Torrence PF. Fan X, et al. Among authors: keith ka. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3224-8. doi: 10.1016/j.bmcl.2006.03.043. Epub 2006 Apr 5. Bioorg Med Chem Lett. 2006. PMID: 16603351

5

5-(Dimethoxymethyl)-2'-deoxyuridine: a novel gem diether nucleoside with anti-orthopoxvirus activity.

Fan X, Zhang X, Zhou L, Keith KA, Kern ER, Torrence PF. Fan X, et al. Among authors: keith ka. J Med Chem. 2006 Jun 1;49(11):3377-82. doi: 10.1021/jm0601710. J Med Chem. 2006. PMID: 16722657 Free PMC article.

6

Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure.

Fan X, Zhang X, Zhou L, Keith KA, Prichard MN, Kern ER, Torrence PF. Fan X, et al. Among authors: keith ka. J Med Chem. 2006 Jul 13;49(14):4052-4. doi: 10.1021/jm060404n. J Med Chem. 2006. PMID: 16821766 Free PMC article.

7

The 4',4'-difluoro analog of 5'-noraristeromycin: a new structural prototype for possible antiviral drug development toward orthopoxvirus and cytomegalovirus.

Roy A, Schneller SW, Keith KA, Hartline CB, Kern ER. Roy A, et al. Among authors: keith ka. Bioorg Med Chem. 2005 Jul 15;13(14):4443-9. doi: 10.1016/j.bmc.2005.04.044. Bioorg Med Chem. 2005. PMID: 15908221

8

Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice.

Quenelle DC, Buller RM, Parker S, Keith KA, Hruby DE, Jordan R, Kern ER. Quenelle DC, et al. Among authors: keith ka. Antimicrob Agents Chemother. 2007 Feb;51(2):689-95. doi: 10.1128/AAC.00879-06. Epub 2006 Nov 20. Antimicrob Agents Chemother. 2007. PMID: 17116683 Free PMC article.

9

Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses.

Quenelle DC, Prichard MN, Keith KA, Hruby DE, Jordan R, Painter GR, Robertson A, Kern ER. Quenelle DC, et al. Among authors: keith ka. Antimicrob Agents Chemother. 2007 Nov;51(11):4118-24. doi: 10.1128/AAC.00762-07. Epub 2007 Aug 27. Antimicrob Agents Chemother. 2007. PMID: 17724153 Free PMC article.

10

In vitro and in vivo evaluation of isatin-beta-thiosemicarbazone and marboran against vaccinia and cowpox virus infections.

Quenelle DC, Keith KA, Kern ER. Quenelle DC, et al. Among authors: keith ka. Antiviral Res. 2006 Aug;71(1):24-30. doi: 10.1016/j.antiviral.2006.02.010. Epub 2006 Mar 29. Antiviral Res. 2006. PMID: 16621041

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