Siddiquee K - Search Results

1

Isoform selective inhibition of STAT1 or STAT3 homo-dimerization via peptidomimetic probes: structural recognition of STAT SH2 domains.

Gunning PT, Katt WP, Glenn M, Siddiquee K, Kim JS, Jove R, Sebti SM, Turkson J, Hamilton AD. Gunning PT, et al. Among authors: siddiquee k. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1875-8. doi: 10.1016/j.bmcl.2007.01.077. Epub 2007 Jan 27. Bioorg Med Chem Lett. 2007. PMID: 17336521

2

Targeting protein-protein interactions: suppression of Stat3 dimerization with rationally designed small-molecule, nonpeptidic SH2 domain binders.

Gunning PT, Glenn MP, Siddiquee KA, Katt WP, Masson E, Sebti SM, Turkson J, Hamilton AD. Gunning PT, et al. Chembiochem. 2008 Nov 24;9(17):2800-3. doi: 10.1002/cbic.200800291. Chembiochem. 2008. PMID: 19006150 Free PMC article. No abstract available.

3

An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.

Siddiquee KA, Gunning PT, Glenn M, Katt WP, Zhang S, Schrock C, Sebti SM, Jove R, Hamilton AD, Turkson J. Siddiquee KA, et al. ACS Chem Biol. 2007 Dec 21;2(12):787-98. doi: 10.1021/cb7001973. ACS Chem Biol. 2007. PMID: 18154266

4

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.

Siddiquee K, Zhang S, Guida WC, Blaskovich MA, Greedy B, Lawrence HR, Yip ML, Jove R, McLaughlin MM, Lawrence NJ, Sebti SM, Turkson J. Siddiquee K, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7391-6. doi: 10.1073/pnas.0609757104. Epub 2007 Apr 26. Proc Natl Acad Sci U S A. 2007. PMID: 17463090 Free PMC article.

5

Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.

Kotha A, Sekharam M, Cilenti L, Siddiquee K, Khaled A, Zervos AS, Carter B, Turkson J, Jove R. Kotha A, et al. Among authors: siddiquee k. Mol Cancer Ther. 2006 Mar;5(3):621-9. doi: 10.1158/1535-7163.MCT-05-0268. Mol Cancer Ther. 2006. PMID: 16546976

6

In Vivo Rapid Assessment of Compound Exposure (RACE) for Profiling the Pharmacokinetics of Novel Chemical Probes.

McAnally D, Vicchiarelli M, Siddiquee K, Smith LH. McAnally D, et al. Among authors: siddiquee k. Curr Protoc Chem Biol. 2012 Dec 1;4(4):299-309. doi: 10.1002/9780470559277.ch120072. Curr Protoc Chem Biol. 2012. PMID: 23788556 Free PMC article.

7

Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization.

McAnally D, Siddiquee K, Gomaa A, Szabo A, Vasile S, Maloney PR, Divlianska DB, Peddibhotla S, Morfa CJ, Hershberger P, Falter R, Williamson R, Terry DB, Farjo R, Pinkerton AB, Qi X, Quigley J, Boulton ME, Grant MB, Smith LH. McAnally D, et al. Among authors: siddiquee k. PLoS One. 2018 Sep 12;13(9):e0202436. doi: 10.1371/journal.pone.0202436. eCollection 2018. PLoS One. 2018. PMID: 30208056 Free PMC article.

8

A Systematic Approach to Identify Biased Agonists of the Apelin Receptor through High-Throughput Screening.

McAnally D, Siddiquee K, Sharir H, Qi F, Phatak S, Li JL, Berg E, Fishman J, Smith L. McAnally D, et al. Among authors: siddiquee k. SLAS Discov. 2017 Aug;22(7):867-878. doi: 10.1177/2472555217699158. Epub 2017 Mar 17. SLAS Discov. 2017. PMID: 28314120 Free article.

9

Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production.

Siddiquee K, Hampton J, Khan S, Zadory D, Gleaves L, Vaughan DE, Smith LH. Siddiquee K, et al. J Hypertens. 2011 Apr;29(4):724-31. doi: 10.1097/HJH.0b013e32834347de. J Hypertens. 2011. PMID: 21358420 Free PMC article.

10

The apelin receptor inhibits the angiotensin II type 1 receptor via allosteric trans-inhibition.

Siddiquee K, Hampton J, McAnally D, May L, Smith L. Siddiquee K, et al. Br J Pharmacol. 2013 Mar;168(5):1104-17. doi: 10.1111/j.1476-5381.2012.02192.x. Br J Pharmacol. 2013. PMID: 22935142 Free PMC article.

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