Tyndale RF - Search Results

1

The pharmacogenetics research network: from SNP discovery to clinical drug response.

Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.

2

Deficient C-oxidation of nicotine continued.

Benowitz NL, Griffin C, Tyndale R. Benowitz NL, et al. Clin Pharmacol Ther. 2001 Dec;70(6):567. doi: 10.1067/mcp.2001.120252. Clin Pharmacol Ther. 2001. PMID: 11753274 No abstract available.

3

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.

Dempsey D, Tutka P, Jacob P 3rd, Allen F, Schoedel K, Tyndale RF, Benowitz NL. Dempsey D, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2004 Jul;76(1):64-72. doi: 10.1016/j.clpt.2004.02.011. Clin Pharmacol Ther. 2004. PMID: 15229465

4

Pharmacogenetics of nicotine metabolism in twins: methods and procedures.

Swan GE, Benowitz NL, Jacob P 3rd, Lessov CN, Tyndale RF, Wilhelmsen K, Krasnow RE, McElroy MR, Moore SE, Wambach M. Swan GE, et al. Among authors: tyndale rf. Twin Res. 2004 Oct;7(5):435-48. doi: 10.1375/1369052042335269. Twin Res. 2004. PMID: 15527659

5

Nicotine metabolism: the impact of CYP2A6 on estimates of additive genetic influence.

Swan GE, Benowitz NL, Lessov CN, Jacob P 3rd, Tyndale RF, Wilhelmsen K. Swan GE, et al. Among authors: tyndale rf. Pharmacogenet Genomics. 2005 Feb;15(2):115-25. doi: 10.1097/01213011-200502000-00007. Pharmacogenet Genomics. 2005. PMID: 15861035

6

Characterization of the novel CYP2A6*21 allele using in vivo nicotine kinetics.

Al Koudsi N, Mwenifumbo JC, Sellers EM, Benowitz NL, Swan GE, Tyndale RF. Al Koudsi N, et al. Among authors: tyndale rf. Eur J Clin Pharmacol. 2006 Jun;62(6):481-4. doi: 10.1007/s00228-006-0113-3. Epub 2006 Apr 28. Eur J Clin Pharmacol. 2006. PMID: 16758265

7

Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation.

Lerman C, Tyndale R, Patterson F, Wileyto EP, Shields PG, Pinto A, Benowitz N. Lerman C, et al. Clin Pharmacol Ther. 2006 Jun;79(6):600-8. doi: 10.1016/j.clpt.2006.02.006. Epub 2006 May 11. Clin Pharmacol Ther. 2006. PMID: 16765148 Clinical Trial.

8

CYP2A6 genotype and the metabolism and disposition kinetics of nicotine.

Benowitz NL, Swan GE, Jacob P 3rd, Lessov-Schlaggar CN, Tyndale RF. Benowitz NL, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2006 Nov;80(5):457-67. doi: 10.1016/j.clpt.2006.08.011. Clin Pharmacol Ther. 2006. PMID: 17112802 Clinical Trial.

9

Identification of novel CYP2A6*1B variants: the CYP2A6*1B allele is associated with faster in vivo nicotine metabolism.

Mwenifumbo JC, Lessov-Schlaggar CN, Zhou Q, Krasnow RE, Swan GE, Benowitz NL, Tyndale RF. Mwenifumbo JC, et al. Among authors: tyndale rf. Clin Pharmacol Ther. 2008 Jan;83(1):115-21. doi: 10.1038/sj.clpt.6100246. Epub 2007 May 23. Clin Pharmacol Ther. 2008. PMID: 17522595 Free PMC article. Clinical Trial.

10

Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism.

Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P 3rd, Tyndale RF, Swan GE, Benowitz NL. Ring HZ, et al. Among authors: tyndale rf. Pharmacogenet Genomics. 2007 Dec;17(12):1007-15. doi: 10.1097/01.fpc.0000220560.59972.33. Pharmacogenet Genomics. 2007. PMID: 18004205

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