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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis.
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K. Phillips HS, et al. Among authors: soroceanu l. Cancer Cell. 2006 Mar;9(3):157-73. doi: 10.1016/j.ccr.2006.02.019. Cancer Cell. 2006. PMID: 16530701 Free article.
PHIP drives glioblastoma motility and invasion by regulating the focal adhesion complex.
de Semir D, Bezrookove V, Nosrati M, Scanlon KR, Singer E, Judkins J, Rieken C, Wu C, Shen J, Schmudermayer C, Dar AA, Miller JR 3rd, Cobbs C, Yount G, Desprez PY, Debs RJ, Salomonis N, McAllister S, Cleaver JE, Soroceanu L, Kashani-Sabet M. de Semir D, et al. Among authors: soroceanu l. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9064-9073. doi: 10.1073/pnas.1914505117. Epub 2020 Apr 9. Proc Natl Acad Sci U S A. 2020. PMID: 32273388 Free PMC article.
A Cell-Surface Membrane Protein Signature for Glioblastoma.
Ghosh D, Funk CC, Caballero J, Shah N, Rouleau K, Earls JC, Soroceanu L, Foltz G, Cobbs CS, Price ND, Hood L. Ghosh D, et al. Among authors: soroceanu l. Cell Syst. 2017 May 24;4(5):516-529.e7. doi: 10.1016/j.cels.2017.03.004. Epub 2017 Mar 29. Cell Syst. 2017. PMID: 28365151 Free PMC article.
Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Dar AA, Bezrookove V, Nosrati M, Ice R, Patino JM, Vaquero EM, Parrett B, Leong SP, Kim KB, Debs RJ, Soroceanu L, Miller JR 3rd, Desprez PY, Cleaver JE, Salomonis N, McAllister S, Kashani-Sabet M. Dar AA, et al. Among authors: soroceanu l. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206824119. doi: 10.1073/pnas.2206824119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969744 Free PMC article.
PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer.
de Semir D, Bezrookove V, Nosrati M, Dar AA, Wu C, Shen J, Rieken C, Venkatasubramanian M, Miller JR 3rd, Desprez PY, McAllister S, Soroceanu L, Debs RJ, Salomonis N, Schadendorf D, Cleaver JE, Kashani-Sabet M. de Semir D, et al. Among authors: soroceanu l. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5766-E5775. doi: 10.1073/pnas.1804779115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866840 Free PMC article.
53 results