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ADAMTS-4 (aggrecanase-1): N-terminal activation mechanisms.
Tortorella MD, Arner EC, Hills R, Gormley J, Fok K, Pegg L, Munie G, Malfait AM. Tortorella MD, et al. Among authors: hills r. Arch Biochem Biophys. 2005 Dec 1;444(1):34-44. doi: 10.1016/j.abb.2005.09.018. Epub 2005 Oct 26. Arch Biochem Biophys. 2005. PMID: 16289022
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate.
Hills R, Mazzarella R, Fok K, Liu M, Nemirovskiy O, Leone J, Zack MD, Arner EC, Viswanathan M, Abujoub A, Muruganandam A, Sexton DJ, Bassill GJ, Sato AK, Malfait AM, Tortorella MD. Hills R, et al. J Biol Chem. 2007 Apr 13;282(15):11101-9. doi: 10.1074/jbc.M611588200. Epub 2007 Feb 20. J Biol Chem. 2007. PMID: 17311924 Free article.
High resolution crystal structure of the catalytic domain of ADAMTS-5 (aggrecanase-2).
Shieh HS, Mathis KJ, Williams JM, Hills RL, Wiese JF, Benson TE, Kiefer JR, Marino MH, Carroll JN, Leone JW, Malfait AM, Arner EC, Tortorella MD, Tomasselli A. Shieh HS, et al. Among authors: hills rl. J Biol Chem. 2008 Jan 18;283(3):1501-1507. doi: 10.1074/jbc.M705879200. Epub 2007 Nov 8. J Biol Chem. 2008. PMID: 17991750 Free article.
Intra-articular injection of tumor necrosis factor-alpha in the rat: an acute and reversible in vivo model of cartilage proteoglycan degradation.
Malfait AM, Tortorella M, Thompson J, Hills R, Meyer DM, Jaffee BD, Chinn K, Ghoreishi-Haack N, Markosyan S, Arner EC. Malfait AM, et al. Among authors: hills r. Osteoarthritis Cartilage. 2009 May;17(5):627-35. doi: 10.1016/j.joca.2008.10.005. Epub 2008 Nov 1. Osteoarthritis Cartilage. 2009. PMID: 19026578 Free article.
335 results