Begley DJ - Search Results

1

Central nervous system drug disposition: the relationship between in situ brain permeability and brain free fraction.

Summerfield SG, Read K, Begley DJ, Obradovic T, Hidalgo IJ, Coggon S, Lewis AV, Porter RA, Jeffrey P. Summerfield SG, et al. Among authors: begley dj. J Pharmacol Exp Ther. 2007 Jul;322(1):205-13. doi: 10.1124/jpet.107.121525. Epub 2007 Apr 3. J Pharmacol Exp Ther. 2007. PMID: 17405866 Free article.

2

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

Begley DJ. Begley DJ. Pharmacol Ther. 2004 Oct;104(1):29-45. doi: 10.1016/j.pharmthera.2004.08.001. Pharmacol Ther. 2004. PMID: 15500907 Review.

3

The blood-brain barrier: principles for targeting peptides and drugs to the central nervous system.

Begley DJ. Begley DJ. J Pharm Pharmacol. 1996 Feb;48(2):136-46. doi: 10.1111/j.2042-7158.1996.tb07112.x. J Pharm Pharmacol. 1996. PMID: 8935161 Review.

4

Intrathecal delivery of protein therapeutics to the brain: a critical reassessment.

Calias P, Banks WA, Begley D, Scarpa M, Dickson P. Calias P, et al. Pharmacol Ther. 2014 Nov;144(2):114-22. doi: 10.1016/j.pharmthera.2014.05.009. Epub 2014 May 20. Pharmacol Ther. 2014. PMID: 24854599 Free article. Review.

5

The effect of drug lipophilicity on P-glycoprotein-mediated colchicine efflux at the blood-brain barrier.

Khan EU, Reichel A, Begley DJ, Roffey SJ, Jezequel SG, Abbott NJ. Khan EU, et al. Among authors: begley dj. Int J Clin Pharmacol Ther. 1998 Feb;36(2):84-6. Int J Clin Pharmacol Ther. 1998. PMID: 9520152 No abstract available.

6

Immunologic privilege in the central nervous system and the blood-brain barrier.

Muldoon LL, Alvarez JI, Begley DJ, Boado RJ, Del Zoppo GJ, Doolittle ND, Engelhardt B, Hallenbeck JM, Lonser RR, Ohlfest JR, Prat A, Scarpa M, Smeyne RJ, Drewes LR, Neuwelt EA. Muldoon LL, et al. Among authors: begley dj. J Cereb Blood Flow Metab. 2013 Jan;33(1):13-21. doi: 10.1038/jcbfm.2012.153. Epub 2012 Oct 17. J Cereb Blood Flow Metab. 2013. PMID: 23072749 Free PMC article. Review.

7

Flavonoid permeability across an in situ model of the blood-brain barrier.

Youdim KA, Qaiser MZ, Begley DJ, Rice-Evans CA, Abbott NJ. Youdim KA, et al. Among authors: begley dj. Free Radic Biol Med. 2004 Mar 1;36(5):592-604. doi: 10.1016/j.freeradbiomed.2003.11.023. Free Radic Biol Med. 2004. PMID: 14980703

8

Determinants of passive drug entry into the central nervous system.

Habgood MD, Begley DJ, Abbott NJ. Habgood MD, et al. Among authors: begley dj. Cell Mol Neurobiol. 2000 Apr;20(2):231-53. doi: 10.1023/a:1007001923498. Cell Mol Neurobiol. 2000. PMID: 10696512 Review.

9

Understanding and circumventing the blood-brain barrier.

Begley DJ. Begley DJ. Acta Paediatr Suppl. 2003 Dec;92(443):83-91. doi: 10.1111/j.1651-2227.2003.tb00226.x. Acta Paediatr Suppl. 2003. PMID: 14989470

10

Potential of immobilized artificial membranes for predicting drug penetration across the blood-brain barrier.

Reichel A, Begley DJ. Reichel A, et al. Among authors: begley dj. Pharm Res. 1998 Aug;15(8):1270-4. doi: 10.1023/a:1011904311149. Pharm Res. 1998. PMID: 9706060

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