Sorensen PH - Search Results

1

Cellular transformation and activation of the phosphoinositide-3-kinase-Akt cascade by the ETV6-NTRK3 chimeric tyrosine kinase requires c-Src.

Jin W, Yun C, Hobbie A, Martin MJ, Sorensen PH, Kim SJ. Jin W, et al. Among authors: sorensen ph. Cancer Res. 2007 Apr 1;67(7):3192-200. doi: 10.1158/0008-5472.CAN-06-3526. Cancer Res. 2007. PMID: 17409427

2

ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma.

Knezevich SR, Garnett MJ, Pysher TJ, Beckwith JB, Grundy PE, Sorensen PH. Knezevich SR, et al. Among authors: sorensen ph. Cancer Res. 1998 Nov 15;58(22):5046-8. Cancer Res. 1998. PMID: 9823307

3

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein.

Hahm KB, Cho K, Lee C, Im YH, Chang J, Choi SG, Sorensen PH, Thiele CJ, Kim SJ. Hahm KB, et al. Among authors: sorensen ph. Nat Genet. 1999 Oct;23(2):222-7. doi: 10.1038/13854. Nat Genet. 1999. PMID: 10508522

4

EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.

Im YH, Kim HT, Lee C, Poulin D, Welford S, Sorensen PH, Denny CT, Kim SJ. Im YH, et al. Among authors: sorensen ph. Cancer Res. 2000 Mar 15;60(6):1536-40. Cancer Res. 2000. PMID: 10749119

5

The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.

Tognon C, Garnett M, Kenward E, Kay R, Morrison K, Sorensen PH. Tognon C, et al. Among authors: sorensen ph. Cancer Res. 2001 Dec 15;61(24):8909-16. Cancer Res. 2001. PMID: 11751416

6

A highly conserved NTRK3 C-terminal sequence in the ETV6-NTRK3 oncoprotein binds the phosphotyrosine binding domain of insulin receptor substrate-1: an essential interaction for transformation.

Lannon CL, Martin MJ, Tognon CE, Jin W, Kim SJ, Sorensen PH. Lannon CL, et al. Among authors: sorensen ph. J Biol Chem. 2004 Feb 20;279(8):6225-34. doi: 10.1074/jbc.M307388200. Epub 2003 Dec 9. J Biol Chem. 2004. PMID: 14668342 Free article.

7

A fluorescence in situ hybridization study of ETV6-NTRK3 fusion gene in secretory breast carcinoma.

Makretsov N, He M, Hayes M, Chia S, Horsman DE, Sorensen PH, Huntsman DG. Makretsov N, et al. Among authors: sorensen ph. Genes Chromosomes Cancer. 2004 Jun;40(2):152-7. doi: 10.1002/gcc.20028. Genes Chromosomes Cancer. 2004. PMID: 15101049

8

Selective usage of D-Type cyclins by Ewing's tumors and rhabdomyosarcomas.

Zhang J, Hu S, Schofield DE, Sorensen PH, Triche TJ. Zhang J, et al. Among authors: sorensen ph. Cancer Res. 2004 Sep 1;64(17):6026-34. doi: 10.1158/0008-5472.CAN-03-2594. Cancer Res. 2004. PMID: 15342383

9

ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages.

Lannon CL, Sorensen PH. Lannon CL, et al. Among authors: sorensen ph. Semin Cancer Biol. 2005 Jun;15(3):215-23. doi: 10.1016/j.semcancer.2005.01.003. Semin Cancer Biol. 2005. PMID: 15826836 Review.

10

The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-beta signaling by inactivating the TGF-beta type II receptor.

Jin W, Kim BC, Tognon C, Lee HJ, Patel S, Lannon CL, Maris JM, Triche TJ, Sorensen PH, Kim SJ. Jin W, et al. Among authors: sorensen ph. Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16239-44. doi: 10.1073/pnas.0503137102. Epub 2005 Oct 28. Proc Natl Acad Sci U S A. 2005. PMID: 16258068 Free PMC article.

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