Alanen K - Search Results

1

Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway.

Dagvadorj A, Collins S, Jomain JB, Abdulghani J, Karras J, Zellweger T, Li H, Nurmi M, Alanen K, Mirtti T, Visakorpi T, Bubendorf L, Goffin V, Nevalainen MT. Dagvadorj A, et al. Among authors: alanen k. Endocrinology. 2007 Jul;148(7):3089-101. doi: 10.1210/en.2006-1761. Epub 2007 Apr 5. Endocrinology. 2007. PMID: 17412813 Free article.

2

Stat3 promotes metastatic progression of prostate cancer.

Abdulghani J, Gu L, Dagvadorj A, Lutz J, Leiby B, Bonuccelli G, Lisanti MP, Zellweger T, Alanen K, Mirtti T, Visakorpi T, Bubendorf L, Nevalainen MT. Abdulghani J, et al. Among authors: alanen k. Am J Pathol. 2008 Jun;172(6):1717-28. doi: 10.2353/ajpath.2008.071054. Epub 2008 May 15. Am J Pathol. 2008. PMID: 18483213 Free PMC article.

3

Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.

Gu L, Vogiatzi P, Puhr M, Dagvadorj A, Lutz J, Ryder A, Addya S, Fortina P, Cooper C, Leiby B, Dasgupta A, Hyslop T, Bubendorf L, Alanen K, Mirtti T, Nevalainen MT. Gu L, et al. Among authors: alanen k. Endocr Relat Cancer. 2010 May 18;17(2):481-93. doi: 10.1677/ERC-09-0328. Print 2010 Jun. Endocr Relat Cancer. 2010. PMID: 20233708 Free PMC article.

4

N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.

Dagvadorj A, Tan SH, Liao Z, Xie J, Nurmi M, Alanen K, Rui H, Mirtti T, Nevalainen MT. Dagvadorj A, et al. Among authors: alanen k. Int J Biochem Cell Biol. 2010 Dec;42(12):2037-46. doi: 10.1016/j.biocel.2010.09.008. Epub 2010 Sep 18. Int J Biochem Cell Biol. 2010. PMID: 20854925 Free PMC article.

5

Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer.

Gu L, Zhu XH, Visakorpi T, Alanen K, Mirtti T, Edmonston TB, Nevalainen MT. Gu L, et al. Among authors: alanen k. Anal Cell Pathol (Amst). 2010;33(2):55-9. doi: 10.3233/ACP-CLO-2010-0534. Anal Cell Pathol (Amst). 2010. PMID: 20966544 Free PMC article.

6

Nuclear Stat5a/b predicts early recurrence and prostate cancer-specific death in patients treated by radical prostatectomy.

Mirtti T, Leiby BE, Abdulghani J, Aaltonen E, Pavela M, Mamtani A, Alanen K, Egevad L, Granfors T, Josefsson A, Stattin P, Bergh A, Nevalainen MT. Mirtti T, et al. Among authors: alanen k. Hum Pathol. 2013 Mar;44(3):310-9. doi: 10.1016/j.humpath.2012.06.001. Epub 2012 Sep 29. Hum Pathol. 2013. PMID: 23026195 Free PMC article.

7

Pharmacologic suppression of JAK1/2 by JAK1/2 inhibitor AZD1480 potently inhibits IL-6-induced experimental prostate cancer metastases formation.

Gu L, Talati P, Vogiatzi P, Romero-Weaver AL, Abdulghani J, Liao Z, Leiby B, Hoang DT, Mirtti T, Alanen K, Zinda M, Huszar D, Nevalainen MT. Gu L, et al. Among authors: alanen k. Mol Cancer Ther. 2014 May;13(5):1246-58. doi: 10.1158/1535-7163.MCT-13-0605. Epub 2014 Feb 27. Mol Cancer Ther. 2014. PMID: 24577942 Free PMC article.

8

Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.

Ahonen TJ, Xie J, LeBaron MJ, Zhu J, Nurmi M, Alanen K, Rui H, Nevalainen MT. Ahonen TJ, et al. Among authors: alanen k. J Biol Chem. 2003 Jul 18;278(29):27287-92. doi: 10.1074/jbc.M304307200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12719422 Free article.

9

Activation of signal transducer and activator of transcription 5 in human prostate cancer is associated with high histological grade.

Li H, Ahonen TJ, Alanen K, Xie J, LeBaron MJ, Pretlow TG, Ealley EL, Zhang Y, Nurmi M, Singh B, Martikainen PM, Nevalainen MT. Li H, et al. Among authors: alanen k. Cancer Res. 2004 Jul 15;64(14):4774-82. doi: 10.1158/0008-5472.CAN-03-3499. Cancer Res. 2004. PMID: 15256446

10

Arachidonic acid pathway members PLA2G7, HPGD, EPHX2, and CYP4F8 identified as putative novel therapeutic targets in prostate cancer.

Vainio P, Gupta S, Ketola K, Mirtti T, Mpindi JP, Kohonen P, Fey V, Perälä M, Smit F, Verhaegh G, Schalken J, Alanen KA, Kallioniemi O, Iljin K. Vainio P, et al. Among authors: alanen ka. Am J Pathol. 2011 Feb;178(2):525-36. doi: 10.1016/j.ajpath.2010.10.002. Am J Pathol. 2011. PMID: 21281786 Free PMC article.

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