Simonsen A - Search Results

1

Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles.

Simonsen A, Cumming RC, Lindmo K, Galaviz V, Cheng S, Rusten TE, Finley KD. Simonsen A, et al. Genetics. 2007 Jun;176(2):1283-97. doi: 10.1534/genetics.106.065011. Epub 2007 Apr 15. Genetics. 2007. PMID: 17435236 Free PMC article.

2

A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body.

Lindmo K, Simonsen A, Brech A, Finley K, Rusten TE, Stenmark H. Lindmo K, et al. Among authors: simonsen a. Exp Cell Res. 2006 Jul 1;312(11):2018-27. doi: 10.1016/j.yexcr.2006.03.002. Epub 2006 Apr 4. Exp Cell Res. 2006. PMID: 16600212

3

Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila.

Simonsen A, Cumming RC, Finley KD. Simonsen A, et al. Autophagy. 2007 Sep-Oct;3(5):499-501. doi: 10.4161/auto.4604. Epub 2007 Jun 20. Autophagy. 2007. PMID: 17617737

4

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.

Filimonenko M, Stuffers S, Raiborg C, Yamamoto A, Malerød L, Fisher EM, Isaacs A, Brech A, Stenmark H, Simonsen A. Filimonenko M, et al. Among authors: simonsen a. J Cell Biol. 2007 Nov 5;179(3):485-500. doi: 10.1083/jcb.200702115. J Cell Biol. 2007. PMID: 17984323 Free PMC article.

5

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila.

Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Simonsen A, et al. Autophagy. 2008 Feb;4(2):176-84. doi: 10.4161/auto.5269. Epub 2007 Nov 6. Autophagy. 2008. PMID: 18059160

6

Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain.

Nezis IP, Simonsen A, Sagona AP, Finley K, Gaumer S, Contamine D, Rusten TE, Stenmark H, Brech A. Nezis IP, et al. Among authors: simonsen a. J Cell Biol. 2008 Mar 24;180(6):1065-71. doi: 10.1083/jcb.200711108. Epub 2008 Mar 17. J Cell Biol. 2008. PMID: 18347073 Free PMC article.

7

ESCRT functions in autophagy and associated disease.

Rusten TE, Simonsen A. Rusten TE, et al. Among authors: simonsen a. Cell Cycle. 2008 May 1;7(9):1166-72. doi: 10.4161/cc.7.9.5784. Epub 2008 Feb 11. Cell Cycle. 2008. PMID: 18418046 Review.

8

Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates.

Cumming RC, Simonsen A, Finley KD. Cumming RC, et al. Among authors: simonsen a. Methods Enzymol. 2008;451:639-51. doi: 10.1016/S0076-6879(08)03235-7. Methods Enzymol. 2008. PMID: 19185743

9

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy.

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T. Clausen TH, et al. Among authors: simonsen a. Autophagy. 2010 Apr;6(3):330-44. doi: 10.4161/auto.6.3.11226. Epub 2010 Apr 11. Autophagy. 2010. PMID: 20168092

10

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.

Filimonenko M, Isakson P, Finley KD, Anderson M, Jeong H, Melia TJ, Bartlett BJ, Myers KM, Birkeland HC, Lamark T, Krainc D, Brech A, Stenmark H, Simonsen A, Yamamoto A. Filimonenko M, et al. Among authors: simonsen a. Mol Cell. 2010 Apr 23;38(2):265-79. doi: 10.1016/j.molcel.2010.04.007. Mol Cell. 2010. PMID: 20417604 Free PMC article.

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