Zhang ZY - Search Results

1

PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.

Zhang S, Zhang ZY. Zhang S, et al. Among authors: zhang zy. Drug Discov Today. 2007 May;12(9-10):373-81. doi: 10.1016/j.drudis.2007.03.011. Epub 2007 Apr 6. Drug Discov Today. 2007. PMID: 17467573 Review.

2

Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.

Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Sun JP, et al. Among authors: zhang zy. J Biol Chem. 2003 Apr 4;278(14):12406-14. doi: 10.1074/jbc.M212491200. Epub 2003 Jan 23. J Biol Chem. 2003. PMID: 12547827 Free article.

3

PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity.

Zhang ZY, Lee SY. Zhang ZY, et al. Expert Opin Investig Drugs. 2003 Feb;12(2):223-33. doi: 10.1517/13543784.12.2.223. Expert Opin Investig Drugs. 2003. PMID: 12556216 Review.

4

Functional studies of protein tyrosine phosphatases with chemical approaches.

Zhang ZY. Zhang ZY. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):100-7. doi: 10.1016/j.bbapap.2005.09.005. Epub 2005 Sep 29. Biochim Biophys Acta. 2005. PMID: 16226063 Review.

5

Synthesis and cell-based activity of a potent and selective protein tyrosine phosphatase 1B inhibitor prodrug.

Boutselis IG, Yu X, Zhang ZY, Borch RF. Boutselis IG, et al. Among authors: zhang zy. J Med Chem. 2007 Feb 22;50(4):856-64. doi: 10.1021/jm061146x. Epub 2007 Jan 24. J Med Chem. 2007. PMID: 17249650

6

Proteomic approaches to studying protein tyrosine phosphatases.

Liang F, Kumar S, Zhang ZY. Liang F, et al. Among authors: zhang zy. Mol Biosyst. 2007 May;3(5):308-16. doi: 10.1039/b700704n. Epub 2007 Mar 21. Mol Biosyst. 2007. PMID: 17460790 Review.

7

An affinity-based fluorescence polarization assay for protein tyrosine phosphatases.

Zhang S, Chen L, Kumar S, Wu L, Lawrence DS, Zhang ZY. Zhang S, et al. Among authors: zhang zy. Methods. 2007 Jul;42(3):261-7. doi: 10.1016/j.ymeth.2007.02.008. Methods. 2007. PMID: 17532513 Free PMC article.

8

Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.

Yu X, Sun JP, He Y, Guo X, Liu S, Zhou B, Hudmon A, Zhang ZY. Yu X, et al. Among authors: zhang zy. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19767-72. doi: 10.1073/pnas.0706233104. Epub 2007 Dec 3. Proc Natl Acad Sci U S A. 2007. PMID: 18056643 Free PMC article.

9

Targeting PTPs with small molecule inhibitors in cancer treatment.

Jiang ZX, Zhang ZY. Jiang ZX, et al. Among authors: zhang zy. Cancer Metastasis Rev. 2008 Jun;27(2):263-72. doi: 10.1007/s10555-008-9113-3. Cancer Metastasis Rev. 2008. PMID: 18259840 Free PMC article. Review.

10

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.

Cortesio CL, Chan KT, Perrin BJ, Burton NO, Zhang S, Zhang ZY, Huttenlocher A. Cortesio CL, et al. Among authors: zhang s, zhang zy. J Cell Biol. 2008 Mar 10;180(5):957-71. doi: 10.1083/jcb.200708048. J Cell Biol. 2008. PMID: 18332219 Free PMC article.

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