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Cardiotonic steroids on the road to anti-cancer therapy.
Mijatovic T, Van Quaquebeke E, Delest B, Debeir O, Darro F, Kiss R. Mijatovic T, et al. Among authors: kiss r. Biochim Biophys Acta. 2007 Sep;1776(1):32-57. doi: 10.1016/j.bbcan.2007.06.002. Epub 2007 Jul 4. Biochim Biophys Acta. 2007. PMID: 17706876 Review.
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
Van Quaquebeke E, Simon G, André A, Dewelle J, El Yazidi M, Bruyneel F, Tuti J, Nacoulma O, Guissou P, Decaestecker C, Braekman JC, Kiss R, Darro F. Van Quaquebeke E, et al. Among authors: kiss r. J Med Chem. 2005 Feb 10;48(3):849-56. doi: 10.1021/jm049405a. J Med Chem. 2005. PMID: 15689169
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
Van Quaquebeke E, Mahieu T, Dumont P, Dewelle J, Ribaucour F, Simon G, Sauvage S, Gaussin JF, Tuti J, El Yazidi M, Van Vynckt F, Mijatovic T, Lefranc F, Darro F, Kiss R. Van Quaquebeke E, et al. Among authors: kiss r. J Med Chem. 2007 Aug 23;50(17):4122-34. doi: 10.1021/jm070315q. Epub 2007 Jul 21. J Med Chem. 2007. PMID: 17658777
Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells.
Lefranc F, Mijatovic T, Kondo Y, Sauvage S, Roland I, Debeir O, Krstic D, Vasic V, Gailly P, Kondo S, Blanco G, Kiss R. Lefranc F, et al. Among authors: kiss r. Neurosurgery. 2008 Jan;62(1):211-21; discussion 221-2. doi: 10.1227/01.NEU.0000311080.43024.0E. Neurosurgery. 2008. PMID: 18300910
1,011 results