Sharpless NE - Search Results

1

Expression of p16Ink4a compensates for p18Ink4c loss in cyclin-dependent kinase 4/6-dependent tumors and tissues.

Ramsey MR, Krishnamurthy J, Pei XH, Torrice C, Lin W, Carrasco DR, Ligon KL, Xiong Y, Sharpless NE. Ramsey MR, et al. Among authors: sharpless ne. Cancer Res. 2007 May 15;67(10):4732-41. doi: 10.1158/0008-5472.CAN-06-3437. Cancer Res. 2007. PMID: 17510401

2

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

Sharpless NE, Bardeesy N, Lee KH, Carrasco D, Castrillon DH, Aguirre AJ, Wu EA, Horner JW, DePinho RA. Sharpless NE, et al. Nature. 2001 Sep 6;413(6851):86-91. doi: 10.1038/35092592. Nature. 2001. PMID: 11544531

3

p16(INK4a) and p53 deficiency cooperate in tumorigenesis.

Sharpless NE, Alson S, Chan S, Silver DP, Castrillon DH, DePinho RA. Sharpless NE, et al. Cancer Res. 2002 May 15;62(10):2761-5. Cancer Res. 2002. PMID: 12019151

4

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.

Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Bachoo RM, et al. Among authors: sharpless ne. Cancer Cell. 2002 Apr;1(3):269-77. doi: 10.1016/s1535-6108(02)00046-6. Cancer Cell. 2002. PMID: 12086863 Free article.

5

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Bardeesy N, et al. Among authors: sharpless ne. Nature. 2002 Sep 12;419(6903):162-7. doi: 10.1038/nature01045. Nature. 2002. PMID: 12226664 Free article.

6

Array comparative genome hybridization for tumor classification and gene discovery in mouse models of malignant melanoma.

O'Hagan RC, Brennan CW, Strahs A, Zhang X, Kannan K, Donovan M, Cauwels C, Sharpless NE, Wong WH, Chin L. O'Hagan RC, et al. Among authors: sharpless ne. Cancer Res. 2003 Sep 1;63(17):5352-6. Cancer Res. 2003. PMID: 14500367

7

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

Sharpless NE, Ramsey MR, Balasubramanian P, Castrillon DH, DePinho RA. Sharpless NE, et al. Oncogene. 2004 Jan 15;23(2):379-85. doi: 10.1038/sj.onc.1207074. Oncogene. 2004. PMID: 14724566

8

Ink4a/Arf expression is a biomarker of aging.

Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Krishnamurthy J, et al. Among authors: sharpless ne. J Clin Invest. 2004 Nov;114(9):1299-307. doi: 10.1172/JCI22475. J Clin Invest. 2004. PMID: 15520862 Free PMC article.

9

INK4a/ARF: a multifunctional tumor suppressor locus.

Sharpless NE. Sharpless NE. Mutat Res. 2005 Aug 25;576(1-2):22-38. doi: 10.1016/j.mrfmmm.2004.08.021. Mutat Res. 2005. PMID: 15878778 Review.

10

p16INK4a induces an age-dependent decline in islet regenerative potential.

Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S, Sharpless NE. Krishnamurthy J, et al. Among authors: sharpless ne. Nature. 2006 Sep 28;443(7110):453-7. doi: 10.1038/nature05092. Epub 2006 Sep 6. Nature. 2006. PMID: 16957737

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