Prakash C - Search Results

1

Metabolism and excretion of CP-122,721, a non-peptide antagonist of the neurokinin NK1 receptor, in dogs: identification of the novel cleaved product 5-trifluoromethoxy salicylic acid in plasma.

Kamel A, Du Y, Colizza K, Prakash C. Kamel A, et al. Among authors: prakash c. Xenobiotica. 2007 May;37(5):559-78. doi: 10.1080/00498250701278434. Xenobiotica. 2007. PMID: 17523057

2

Characterization of a novel metabolite intermediate of ziprasidone in hepatic cytosolic fractions of rat, dog, and human by ESI-MS/MS, hydrogen/deuterium exchange, and chemical derivatization.

Miao Z, Kamel A, Prakash C. Miao Z, et al. Among authors: prakash c. Drug Metab Dispos. 2005 Jul;33(7):879-83. doi: 10.1124/dmd.105.004036. Epub 2005 Apr 8. Drug Metab Dispos. 2005. PMID: 15821046

3

Characterization of metabolites of a NK1 receptor antagonist, CJ-11,972, in human liver microsomes and recombinant human CYP isoforms by liquid chromatography/tandem mass spectrometry.

Prakash C, Lin J, Colizza K, Miao Z. Prakash C, et al. Rapid Commun Mass Spectrom. 2007;21(17):2822-32. doi: 10.1002/rcm.3153. Rapid Commun Mass Spectrom. 2007. PMID: 17661339

4

Metabolism and excretion of the novel antipsychotic drug ziprasidone in rats after oral administration of a mixture of 14C- and 3H-labeled ziprasidone.

Prakash C, Kamel A, Anderson W, Howard H. Prakash C, et al. Drug Metab Dispos. 1997 Feb;25(2):206-18. Drug Metab Dispos. 1997. PMID: 9029052

5

Metabolism and excretion of a new antipsychotic drug, ziprasidone, in humans.

Prakash C, Kamel A, Gummerus J, Wilner K. Prakash C, et al. Drug Metab Dispos. 1997 Jul;25(7):863-72. Drug Metab Dispos. 1997. PMID: 9224781 Clinical Trial.

6

Characterization of the novel benzisothiazole ring-cleaved products of the antipsychotic drug ziprasidone.

Prakash C, Kamel A, Cui D. Prakash C, et al. Drug Metab Dispos. 1997 Jul;25(7):897-901. Drug Metab Dispos. 1997. PMID: 9224786

7

Determination of the substance P receptor antagonist CP-122,721 in plasma by narrow-bore high-performance liquid chromatography-ionspray tandem mass spectrometry.

Kamel A, Prakash C. Kamel A, et al. Among authors: prakash c. J Chromatogr B Biomed Sci Appl. 1997 Oct 24;700(1-2):139-46. doi: 10.1016/s0378-4347(97)00315-0. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9390723

8

Metabolism, pharmacokinetics and excretion of a potent tachykinin NK1 receptor antagonist (CP-122,721) in rat: characterization of a novel oxidative pathway.

Kamel A, Davis J, Potchoiba MJ, Prakash C. Kamel A, et al. Among authors: prakash c. Xenobiotica. 2006 Feb-Mar;36(2-3):235-58. doi: 10.1080/00498250600594444. Xenobiotica. 2006. PMID: 16702114

9

High performance liquid chromatography/atmospheric pressure ionization/tandem mass spectrometry (HPLC/API/MS/MS) in drug metabolism and toxicology.

Kamel A, Prakash C. Kamel A, et al. Among authors: prakash c. Curr Drug Metab. 2006 Dec;7(8):837-52. doi: 10.2174/138920006779010593. Curr Drug Metab. 2006. PMID: 17168686 Review.

10

Reduction and methylation of ziprasidone by glutathione, aldehyde oxidase, and thiol S-methyltransferase in humans: an in vitro study.

Obach RS, Prakash C, Kamel AM. Obach RS, et al. Among authors: prakash c. Xenobiotica. 2012 Nov;42(11):1049-57. doi: 10.3109/00498254.2012.683203. Epub 2012 May 4. Xenobiotica. 2012. PMID: 22559212

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