Lazo JS - Search Results

1

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM. Lazo JS, et al. J Pharmacol Exp Ther. 2007 Sep;322(3):940-7. doi: 10.1124/jpet.107.122242. Epub 2007 May 30. J Pharmacol Exp Ther. 2007. PMID: 17538006

2

Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum.

Kondo Y, Kuo SM, Lazo JS. Kondo Y, et al. Among authors: lazo js. J Pharmacol Exp Ther. 1994 Sep;270(3):1313-8. J Pharmacol Exp Ther. 1994. PMID: 7932184

3

Combinatorial synthesis and biological evaluation of library of small-molecule Ser/Thr-protein phosphatase inhibitors.

Wipf P, Cunningham A, Rice RL, Lazo JS. Wipf P, et al. Among authors: lazo js. Bioorg Med Chem. 1997 Jan;5(1):165-77. doi: 10.1016/s0968-0896(96)00199-x. Bioorg Med Chem. 1997. PMID: 9043668

4

A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation.

Rice RL, Rusnak JM, Yokokawa F, Yokokawa S, Messner DJ, Boynton AL, Wipf P, Lazo JS. Rice RL, et al. Among authors: lazo js. Biochemistry. 1997 Dec 16;36(50):15965-74. doi: 10.1021/bi971338h. Biochemistry. 1997. PMID: 9398331

5

Disruption of insulin-like growth factor-1 signaling and down-regulation of cdc2 by SC-alphaalphadelta9, a novel small molecule antisignaling agent identified in a targeted array library.

Vogt A, Rice RL, Settineri CE, Yokokawa F, Yokokawa S, Wipf P, Lazo JS. Vogt A, et al. Among authors: lazo js. J Pharmacol Exp Ther. 1998 Nov;287(2):806-13. J Pharmacol Exp Ther. 1998. PMID: 9808713

6

Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors.

Wipf P, Aslan DC, Luci DK, Southwick EC, Lazo JS. Wipf P, et al. Among authors: lazo js. Biotechnol Bioeng. 2000 Winter;71(1):58-70. doi: 10.1002/(sici)1097-0290(200024)71:1<58::aid-bit9>3.0.co;2-0. Biotechnol Bioeng. 2000. PMID: 10629537

7

In vivo antitumor activity and induction of insulin-like growth factor-1-resistant apoptosis by SC-alphaalphadelta9.

Vogt A, Wang AS, Johnson CS, Fabisiak JP, Wipf P, Lazo JS. Vogt A, et al. Among authors: lazo js. J Pharmacol Exp Ther. 2000 Feb;292(2):530-7. J Pharmacol Exp Ther. 2000. PMID: 10640289

8

Combinatorial chemistry and contemporary pharmacology.

Lazo JS, Wipf P. Lazo JS, et al. J Pharmacol Exp Ther. 2000 Jun;293(3):705-9. doi: 10.1002/chin.200043259. J Pharmacol Exp Ther. 2000. PMID: 10869367

9

Antitumor imidazolyl disulfide IV-2 causes irreversible G(2)/M cell cycle arrest without hyperphosphorylation of cyclin-dependent kinase Cdk1.

Vogt A, Tamura K, Watson S, Lazo JS. Vogt A, et al. Among authors: lazo js. J Pharmacol Exp Ther. 2000 Sep;294(3):1070-5. J Pharmacol Exp Ther. 2000. PMID: 10945861

10

Antimitotic actions of a novel analog of the fungal metabolite palmarumycin CP1.

Lazo JS, Tamura K, Vogt A, Jung JK, Rodriguez S, Balachandran R, Day BW, Wipf P. Lazo JS, et al. J Pharmacol Exp Ther. 2001 Feb;296(2):364-71. J Pharmacol Exp Ther. 2001. PMID: 11160619

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