Werner S - Search Results

1

Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library.

Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, Yellow-Duke A, Bahar I, Brummond KM. Lazo JS, et al. Among authors: werner s. J Pharmacol Exp Ther. 2007 Sep;322(3):940-7. doi: 10.1124/jpet.107.122242. Epub 2007 May 30. J Pharmacol Exp Ther. 2007. PMID: 17538006

2

Solution-phase synthesis of a tricyclic pyrrole-2-carboxamide discovery library applying a stetter-Paal-Knorr reaction sequence.

Werner S, Iyer PS, Fodor MD, Coleman CM, Twining LA, Mitasev B, Brummond KM. Werner S, et al. J Comb Chem. 2006 May-Jun;8(3):368-80. doi: 10.1021/cc050160c. J Comb Chem. 2006. PMID: 16677007 Free PMC article.

3

Design and synthesis of a 3,4-dehydroproline amide discovery library.

Werner S, Kasi D, Brummond KM. Werner S, et al. J Comb Chem. 2007 Jul-Aug;9(4):677-83. doi: 10.1021/cc070011p. Epub 2007 Jun 14. J Comb Chem. 2007. PMID: 17567173

4

Diverging Rh(I)-catalyzed carbocylization strategy to prepare a library of unique cyclic ethers.

Mao S, Probst D, Werner S, Chen J, Xie X, Brummond KM. Mao S, et al. Among authors: werner s. J Comb Chem. 2008 Mar-Apr;10(2):235-46. doi: 10.1021/cc7001843. Epub 2008 Feb 14. J Comb Chem. 2008. PMID: 18271514

5

Skeletal and Appendage Diversity as Design Elements in the Synthesis of a Discovery Library of Nonaromatic Polycyclic 5-Iminooxazolidin-2-ones, Hydantoins, and Acylureas.

Werner S, Turner DM, Chambers PG, Brummond KM. Werner S, et al. Tetrahedron. 2008 Jul 14;64(29):6997-7007. doi: 10.1016/j.tet.2008.02.033. Tetrahedron. 2008. PMID: 28553003 Free PMC article.

6

A screening method for chiral selectors that does not require covalent attachment.

Chen Z, Yang Y, Werner S, Wipf P, Weber SG. Chen Z, et al. Among authors: werner s. J Am Chem Soc. 2006 Feb 22;128(7):2208-9. doi: 10.1021/ja058004x. J Am Chem Soc. 2006. PMID: 16478163 Free PMC article.

7

Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation.

Wright CM, Chovatiya RJ, Jameson NE, Turner DM, Zhu G, Werner S, Huryn DM, Pipas JM, Day BW, Wipf P, Brodsky JL. Wright CM, et al. Among authors: werner s. Bioorg Med Chem. 2008 Mar 15;16(6):3291-301. doi: 10.1016/j.bmc.2007.12.014. Epub 2007 Dec 14. Bioorg Med Chem. 2008. PMID: 18164205 Free PMC article.

8

Extractive phase vanishing reactions with dichloromethane, perfluorohexanes, and dibromoethane: slow addition in a test tube.

Curran DP, Werner S. Curran DP, et al. Among authors: werner s. Org Lett. 2004 Mar 18;6(6):1021-4. doi: 10.1021/ol0499248. Org Lett. 2004. PMID: 15012090

9

Fluorous dienophiles are powerful diene scavengers in Diels-Alder reactions.

Werner S, Curran DP. Werner S, et al. Org Lett. 2003 Sep 4;5(18):3293-6. doi: 10.1021/ol035214a. Org Lett. 2003. PMID: 12943410

10

Fluorous parallel synthesis of a piperazinedione-fused tricyclic compound library.

Werner S, Nielsen SD, Wipf P, Turner DM, Chambers PG, Geib SJ, Curran DP, Zhang W. Werner S, et al. J Comb Chem. 2009 May-Jun;11(3):452-9. doi: 10.1021/cc900003q. J Comb Chem. 2009. PMID: 19301852 Free PMC article.

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