Silengo S - Search Results

1

Glycosylation of the dengue 2 virus E protein at N67 is critical for virus growth in vitro but not for growth in intrathoracically inoculated Aedes aegypti mosquitoes.

Bryant JE, Calvert AE, Mesesan K, Crabtree MB, Volpe KE, Silengo S, Kinney RM, Huang CY, Miller BR, Roehrig JT. Bryant JE, et al. Among authors: silengo s. Virology. 2007 Sep 30;366(2):415-23. doi: 10.1016/j.virol.2007.05.007. Epub 2007 Jun 1. Virology. 2007. PMID: 17543367 Free article.

2

Chimeric dengue 2 PDK-53/West Nile NY99 viruses retain the phenotypic attenuation markers of the candidate PDK-53 vaccine virus and protect mice against lethal challenge with West Nile virus.

Huang CY, Silengo SJ, Whiteman MC, Kinney RM. Huang CY, et al. Among authors: silengo sj. J Virol. 2005 Jun;79(12):7300-10. doi: 10.1128/JVI.79.12.7300-7310.2005. J Virol. 2005. PMID: 15919884 Free PMC article.

3

The dengue virus type 2 envelope protein fusion peptide is essential for membrane fusion.

Huang CY, Butrapet S, Moss KJ, Childers T, Erb SM, Calvert AE, Silengo SJ, Kinney RM, Blair CD, Roehrig JT. Huang CY, et al. Among authors: silengo sj. Virology. 2010 Jan 20;396(2):305-15. doi: 10.1016/j.virol.2009.10.027. Epub 2009 Nov 12. Virology. 2010. PMID: 19913272 Free article.

4

Domain-III FG loop of the dengue virus type 2 envelope protein is important for infection of mammalian cells and Aedes aegypti mosquitoes.

Erb SM, Butrapet S, Moss KJ, Luy BE, Childers T, Calvert AE, Silengo SJ, Roehrig JT, Huang CY, Blair CD. Erb SM, et al. Among authors: silengo sj. Virology. 2010 Oct 25;406(2):328-35. doi: 10.1016/j.virol.2010.07.024. Epub 2010 Aug 13. Virology. 2010. PMID: 20708768 Free article.

5

Genetic and phenotypic characterization of manufacturing seeds for a tetravalent dengue vaccine (DENVax).

Huang CY, Kinney RM, Livengood JA, Bolling B, Arguello JJ, Luy BE, Silengo SJ, Boroughs KL, Stovall JL, Kalanidhi AP, Brault AC, Osorio JE, Stinchcomb DT. Huang CY, et al. Among authors: silengo sj. PLoS Negl Trop Dis. 2013 May 30;7(5):e2243. doi: 10.1371/journal.pntd.0002243. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23738026 Free PMC article.

6

Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.

Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM. Stein DA, et al. Among authors: silengo s. J Antimicrob Chemother. 2008 Sep;62(3):555-65. doi: 10.1093/jac/dkn221. Epub 2008 Jun 19. J Antimicrob Chemother. 2008. PMID: 18567576 Free PMC article.

7

Novel formulations enhance the thermal stability of live-attenuated flavivirus vaccines.

Wiggan O, Livengood JA, Silengo SJ, Kinney RM, Osorio JE, Huang CY, Stinchcomb DT. Wiggan O, et al. Among authors: silengo sj. Vaccine. 2011 Oct 6;29(43):7456-62. doi: 10.1016/j.vaccine.2011.07.054. Epub 2011 Jul 29. Vaccine. 2011. PMID: 21803103 Free PMC article.

8

Safety and immunogenicity of a recombinant live attenuated tetravalent dengue vaccine (DENVax) in flavivirus-naive healthy adults in Colombia: a randomised, placebo-controlled, phase 1 study.

Osorio JE, Velez ID, Thomson C, Lopez L, Jimenez A, Haller AA, Silengo S, Scott J, Boroughs KL, Stovall JL, Luy BE, Arguello J, Beatty ME, Santangelo J, Gordon GS, Huang CY, Stinchcomb DT. Osorio JE, et al. Among authors: silengo s. Lancet Infect Dis. 2014 Sep;14(9):830-8. doi: 10.1016/S1473-3099(14)70811-4. Epub 2014 Jul 23. Lancet Infect Dis. 2014. PMID: 25087476 Free PMC article. Clinical Trial.

9

Efficacy of a tetravalent chimeric dengue vaccine (DENVax) in Cynomolgus macaques.

Osorio JE, Brewoo JN, Silengo SJ, Arguello J, Moldovan IR, Tary-Lehmann M, Powell TD, Livengood JA, Kinney RM, Huang CY, Stinchcomb DT. Osorio JE, et al. Among authors: silengo sj. Am J Trop Med Hyg. 2011 Jun;84(6):978-87. doi: 10.4269/ajtmh.2011.10-0592. Am J Trop Med Hyg. 2011. PMID: 21633037 Free PMC article.

10

Immunogenicity and efficacy of chimeric dengue vaccine (DENVax) formulations in interferon-deficient AG129 mice.

Brewoo JN, Kinney RM, Powell TD, Arguello JJ, Silengo SJ, Partidos CD, Huang CY, Stinchcomb DT, Osorio JE. Brewoo JN, et al. Among authors: silengo sj. Vaccine. 2012 Feb 14;30(8):1513-20. doi: 10.1016/j.vaccine.2011.11.072. Epub 2011 Dec 13. Vaccine. 2012. PMID: 22178727 Free PMC article.

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