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A microRNA component of the p53 tumour suppressor network.
He L, He X, Lim LP, de Stanchina E, Xuan Z, Liang Y, Xue W, Zender L, Magnus J, Ridzon D, Jackson AL, Linsley PS, Chen C, Lowe SW, Cleary MA, Hannon GJ. He L, et al. Among authors: he x. Nature. 2007 Jun 28;447(7148):1130-4. doi: 10.1038/nature05939. Epub 2007 Jun 6. Nature. 2007. PMID: 17554337 Free PMC article.
miR-34 miRNAs provide a barrier for somatic cell reprogramming.
Choi YJ, Lin CP, Ho JJ, He X, Okada N, Bu P, Zhong Y, Kim SY, Bennett MJ, Chen C, Ozturk A, Hicks GG, Hannon GJ, He L. Choi YJ, et al. Among authors: he x, he l. Nat Cell Biol. 2011 Oct 23;13(11):1353-60. doi: 10.1038/ncb2366. Nat Cell Biol. 2011. PMID: 22020437 Free PMC article.
A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.
Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L. Okada N, et al. Among authors: he x, he l, he b. Genes Dev. 2014 Mar 1;28(5):438-50. doi: 10.1101/gad.233585.113. Epub 2014 Feb 14. Genes Dev. 2014. PMID: 24532687 Free PMC article.
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