Holt LJ - Search Results

1

Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Smith FM, Holt LJ, Garfield AS, Charalambous M, Koumanov F, Perry M, Bazzani R, Sheardown SA, Hegarty BD, Lyons RJ, Cooney GJ, Daly RJ, Ward A. Smith FM, et al. Among authors: holt lj. Mol Cell Biol. 2007 Aug;27(16):5871-86. doi: 10.1128/MCB.02087-06. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562854 Free PMC article.

2

Adapter protein connections: the MRL and Grb7 protein families.

Holt LJ, Daly RJ. Holt LJ, et al. Growth Factors. 2005 Sep;23(3):193-201. doi: 10.1080/08977190500196267. Growth Factors. 2005. PMID: 16243711 Review. No abstract available.

3

Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14.

Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR. Depetris RS, et al. Among authors: holt lj. Mol Cell. 2005 Oct 28;20(2):325-33. doi: 10.1016/j.molcel.2005.09.001. Mol Cell. 2005. PMID: 16246733 Free PMC article.

4

Molecular determinants of Grb14-mediated inhibition of insulin signaling.

Goenaga D, Hampe C, Carré N, Cailliau K, Browaeys-Poly E, Perdereau D, Holt LJ, Daly RJ, Girard J, Broutin I, Issad T, Burnol AF. Goenaga D, et al. Among authors: holt lj. Mol Endocrinol. 2009 Jul;23(7):1043-51. doi: 10.1210/me.2008-0360. Epub 2009 Apr 9. Mol Endocrinol. 2009. PMID: 19359342 Free PMC article.

5

Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation.

Rajala A, Daly RJ, Tanito M, Allen DT, Holt LJ, Lobanova ES, Arshavsky VY, Rajala RV. Rajala A, et al. Among authors: holt lj. Biochemistry. 2009 Jun 23;48(24):5563-72. doi: 10.1021/bi9000062. Biochemistry. 2009. PMID: 19438210 Free PMC article.

6

Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis.

Holt LJ, Lyons RJ, Ryan AS, Beale SM, Ward A, Cooney GJ, Daly RJ. Holt LJ, et al. Mol Endocrinol. 2009 Sep;23(9):1406-14. doi: 10.1210/me.2008-0386. Epub 2009 Jun 18. Mol Endocrinol. 2009. PMID: 19541746 Free PMC article.

7

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.

Berg JS, Lin KK, Sonnet C, Boles NC, Weksberg DC, Nguyen H, Holt LJ, Rickwood D, Daly RJ, Goodell MA. Berg JS, et al. Among authors: holt lj. PLoS One. 2011;6(10):e26410. doi: 10.1371/journal.pone.0026410. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22039481 Free PMC article.

8

Grb10 regulates the development of fiber number in skeletal muscle.

Holt LJ, Turner N, Mokbel N, Trefely S, Kanzleiter T, Kaplan W, Ormandy CJ, Daly RJ, Cooney GJ. Holt LJ, et al. FASEB J. 2012 Sep;26(9):3658-69. doi: 10.1096/fj.11-199349. Epub 2012 May 23. FASEB J. 2012. PMID: 22623587

9

Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.

Mokbel N, Hoffman NJ, Girgis CM, Small L, Turner N, Daly RJ, Cooney GJ, Holt LJ. Mokbel N, et al. Among authors: holt lj. J Cell Physiol. 2014 Nov;229(11):1753-64. doi: 10.1002/jcp.24628. J Cell Physiol. 2014. PMID: 24664951

10

Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice.

Holt LJ, Brandon AE, Small L, Suryana E, Preston E, Wilks D, Mokbel N, Coles CA, White JD, Turner N, Daly RJ, Cooney GJ. Holt LJ, et al. Endocrinology. 2018 Mar 1;159(3):1339-1351. doi: 10.1210/en.2017-00851. Endocrinology. 2018. PMID: 29370381

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