Smith FM - Search Results

1

Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.

Smith FM, Holt LJ, Garfield AS, Charalambous M, Koumanov F, Perry M, Bazzani R, Sheardown SA, Hegarty BD, Lyons RJ, Cooney GJ, Daly RJ, Ward A. Smith FM, et al. Mol Cell Biol. 2007 Aug;27(16):5871-86. doi: 10.1128/MCB.02087-06. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562854 Free PMC article.

2

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.

Charalambous M, Smith FM, Bennett WR, Crew TE, Mackenzie F, Ward A. Charalambous M, et al. Among authors: smith fm. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8292-7. doi: 10.1073/pnas.1532175100. Epub 2003 Jun 26. Proc Natl Acad Sci U S A. 2003. PMID: 12829789 Free PMC article.

3

Regulation of growth and metabolism by imprinted genes.

Smith FM, Garfield AS, Ward A. Smith FM, et al. Cytogenet Genome Res. 2006;113(1-4):279-91. doi: 10.1159/000090843. Cytogenet Genome Res. 2006. PMID: 16575191 Review.

4

Maternally-inherited Grb10 reduces placental size and efficiency.

Charalambous M, Cowley M, Geoghegan F, Smith FM, Radford EJ, Marlow BP, Graham CF, Hurst LD, Ward A. Charalambous M, et al. Among authors: smith fm. Dev Biol. 2010 Jan 1;337(1):1-8. doi: 10.1016/j.ydbio.2009.10.011. Epub 2009 Oct 13. Dev Biol. 2010. PMID: 19833122 Free article.

5

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10.

Garfield AS, Cowley M, Smith FM, Moorwood K, Stewart-Cox JE, Gilroy K, Baker S, Xia J, Dalley JW, Hurst LD, Wilkinson LS, Isles AR, Ward A. Garfield AS, et al. Among authors: smith fm. Nature. 2011 Jan 27;469(7331):534-8. doi: 10.1038/nature09651. Nature. 2011. PMID: 21270893 Free PMC article.

6

Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes.

Moorwood K, Smith FM, Garfield AS, Ward A. Moorwood K, et al. Among authors: smith fm. BMC Biol. 2024 May 30;22(1):127. doi: 10.1186/s12915-024-01926-w. BMC Biol. 2024. PMID: 38816743 Free PMC article.

7

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism.

Moorwood K, Smith FM, Garfield AS, Cowley M, Holt LJ, Daly RJ, Ward A. Moorwood K, et al. Among authors: smith fm. BMC Biol. 2024 Sep 30;22(1):221. doi: 10.1186/s12915-024-02018-5. BMC Biol. 2024. PMID: 39343875 Free PMC article.

8

EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation.

Offenhäuser C, Dave KA, Beckett KJ, Smith FM, Jayakody BA, Cooper LT, Agyei-Yeboah H, McCarron JK, Li Y, Bastick K, Al-Ejeh F, Cullen JK, Coulthard MG, Gorman JJ, Boyd AW, Day BW. Offenhäuser C, et al. Among authors: smith fm. Oncogene. 2024 Nov 7. doi: 10.1038/s41388-024-03206-x. Online ahead of print. Oncogene. 2024. PMID: 39511410

9

GATA1-deficient human pluripotent stem cells generate neutrophils with improved antifungal immunity that is mediated by the integrin CD18.

Wagner AS, Smith FM, Bennin DA, Votava JA, Datta R, Giese MA, Zhao W, Skala MC, Fan J, Keller NP, Huttenlocher A. Wagner AS, et al. Among authors: smith fm. bioRxiv [Preprint]. 2024 Oct 11:2024.10.11.617742. doi: 10.1101/2024.10.11.617742. bioRxiv. 2024. PMID: 39416161 Free PMC article. Preprint.

10

Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells-implications for blood-brain barrier physiology in Friedreich's ataxia.

Smith FM, Kosman DJ. Smith FM, et al. Front Mol Biosci. 2024 Jan 11;10:1299201. doi: 10.3389/fmolb.2023.1299201. eCollection 2023. Front Mol Biosci. 2024. PMID: 38274097 Free PMC article.

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