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Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Pellagatti A, Jädersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, Merup M, Nilsson L, Samuelsson J, Sander B, Wainscoat JS, Boultwood J, Hellström-Lindberg E. Pellagatti A, et al. Among authors: boultwood j. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11406-11. doi: 10.1073/pnas.0610477104. Epub 2007 Jun 18. Proc Natl Acad Sci U S A. 2007. PMID: 17576924 Free PMC article.
Homozygous deletion of FMS in a patient with the 5q- syndrome.
Boultwood J, Rack K, Buckle VJ, Kelly S, Madden J, Oscier DG, Wainscoat JS. Boultwood J, et al. Br J Haematol. 1990 Oct;76(2):310-1. doi: 10.1111/j.1365-2141.1990.tb07892.x. Br J Haematol. 1990. PMID: 2094336 No abstract available.
246 results