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Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
Pellagatti A, Jädersten M, Forsblom AM, Cattan H, Christensson B, Emanuelsson EK, Merup M, Nilsson L, Samuelsson J, Sander B, Wainscoat JS, Boultwood J, Hellström-Lindberg E. Pellagatti A, et al. Among authors: sander b. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11406-11. doi: 10.1073/pnas.0610477104. Epub 2007 Jun 18. Proc Natl Acad Sci U S A. 2007. PMID: 17576924 Free PMC article.
The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS.
Hofman IJF, Mortera-Blanco T, Moura PL, Vestlund J, Larsson SV, Elvarsdottir EM, Walldin G, Tobiasson M, Sander B, Dimitriou M, Jacobsen SW, Woll PS, Jädersten M, Hellström-Lindberg E. Hofman IJF, et al. Among authors: sander b. Blood Adv. 2022 Aug 23;6(16):4705-4709. doi: 10.1182/bloodadvances.2022007858. Blood Adv. 2022. PMID: 35728121 Free PMC article. No abstract available.
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.
Sirenko M, Bernard E, Creignou M, Domenico D, Farina A, Arango Ossa JE, Kosmider O, Hasserjian R, Jädersten M, Germing U, Sanz G, van de Loosdrecht AA, Gurnari C, Follo MY, Thol F, Zamora L, Pinheiro RF, Pellagatti A, Elias HK, Haase D, Sander B, Orna E, Zoldan K, Eder LN, Sperr WR, Thalhammer R, Ganster C, Adès L, Tobiasson M, Palomo L, Della Porta MG, Huberman K, Fenaux P, Belickova M, Savona MR, Klimek VM, Santos FPS, Boultwood J, Kotsianidis I, Santini V, Solé F, Platzbecker U, Heuser M, Valent P, Finelli C, Voso MT, Shih LY, Ogawa S, Fontenay M, Jansen JH, Cervera J, Ebert BL, Bejar R, Greenberg PL, Gattermann N, Malcovati L, Cazzola M, Beck DB, Hellström-Lindberg E, Papaemmanuil E. Sirenko M, et al. Among authors: sander b. Blood. 2024 Sep 12;144(11):1221-1229. doi: 10.1182/blood.2023023723. Blood. 2024. PMID: 38687605
704 results