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Page 1
Quinazoline derivatives as MC-I inhibitors: evaluation of myocardial uptake using Positron Emission Tomography in rat and non-human primate.
Purohit A, Benetti R, Hayes M, Guaraldi M, Kagan M, Yalamanchilli P, Su F, Azure M, Mistry M, Yu M, Robinson S, Dischino DD, Casebier D. Purohit A, et al. Among authors: guaraldi m. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4882-5. doi: 10.1016/j.bmcl.2007.06.043. Epub 2007 Jun 14. Bioorg Med Chem Lett. 2007. PMID: 17604167
BMS-747158-02: a novel PET myocardial perfusion imaging agent.
Yu M, Guaraldi MT, Mistry M, Kagan M, McDonald JL, Drew K, Radeke H, Azure M, Purohit A, Casebier DS, Robinson SP. Yu M, et al. Among authors: guaraldi mt. J Nucl Cardiol. 2007 Nov-Dec;14(6):789-98. doi: 10.1016/j.nuclcard.2007.07.008. Epub 2007 Oct 22. J Nucl Cardiol. 2007. PMID: 18022105
Synthesis and biological evaluation of the mitochondrial complex 1 inhibitor 2-[4-(4-fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a potential cardiac positron emission tomography tracer.
Radeke H, Hanson K, Yalamanchili P, Hayes M, Zhang ZQ, Azure M, Yu M, Guaraldi M, Kagan M, Robinson S, Casebier D. Radeke H, et al. Among authors: guaraldi m. J Med Chem. 2007 Sep 6;50(18):4304-15. doi: 10.1021/jm0701831. Epub 2007 Aug 15. J Med Chem. 2007. PMID: 17696417
Assessment of 18F-labeled mitochondrial complex I inhibitors as PET myocardial perfusion imaging agents in rats, rabbits, and primates.
Yu M, Guaraldi M, Kagan M, Mistry M, McDonald J, Bozek J, Yalamanchili P, Hayes M, Azure M, Purohit A, Radeke H, Casebier DS, Robinson SP. Yu M, et al. Among authors: guaraldi m. Eur J Nucl Med Mol Imaging. 2009 Jan;36(1):63-72. doi: 10.1007/s00259-008-0909-8. Epub 2008 Aug 21. Eur J Nucl Med Mol Imaging. 2009. PMID: 18716773
[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents.
Deskus JA, Dischino DD, Mattson RJ, Ditta JL, Parker MF, Denhart DJ, Zuev D, Huang H, Hartz RA, Ahuja VT, Wong H, Mattson GK, Molski TF, Grace JE Jr, Zueva L, Nielsen JM, Dulac H, Li YW, Guaraldi M, Azure M, Onthank D, Hayes M, Wexler E, McDonald J, Lodge NJ, Bronson JJ, Macor JE. Deskus JA, et al. Among authors: guaraldi m. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6651-5. doi: 10.1016/j.bmcl.2012.08.112. Epub 2012 Sep 7. Bioorg Med Chem Lett. 2012. PMID: 23010264
Evaluation of LMI1195, a novel 18F-labeled cardiac neuronal PET imaging agent, in cells and animal models.
Yu M, Bozek J, Lamoy M, Guaraldi M, Silva P, Kagan M, Yalamanchili P, Onthank D, Mistry M, Lazewatsky J, Broekema M, Radeke H, Purohit A, Cdebaca M, Azure M, Cesati R, Casebier D, Robinson SP. Yu M, et al. Among authors: guaraldi m. Circ Cardiovasc Imaging. 2011 Jul;4(4):435-43. doi: 10.1161/CIRCIMAGING.110.962126. Epub 2011 May 9. Circ Cardiovasc Imaging. 2011. PMID: 21555377
49 results