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Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis.
Karahatay S, Thomas K, Koybasi S, Senkal CE, Elojeimy S, Liu X, Bielawski J, Day TA, Gillespie MB, Sinha D, Norris JS, Hannun YA, Ogretmen B. Karahatay S, et al. Among authors: liu x. Cancer Lett. 2007 Oct 18;256(1):101-11. doi: 10.1016/j.canlet.2007.06.003. Epub 2007 Jul 9. Cancer Lett. 2007. PMID: 17619081 Free PMC article. Clinical Trial.
New insights on the use of desipramine as an inhibitor for acid ceramidase.
Elojeimy S, Holman DH, Liu X, El-Zawahry A, Villani M, Cheng JC, Mahdy A, Zeidan Y, Bielwaska A, Hannun YA, Norris JS. Elojeimy S, et al. Among authors: liu x. FEBS Lett. 2006 Aug 21;580(19):4751-6. doi: 10.1016/j.febslet.2006.07.071. Epub 2006 Aug 4. FEBS Lett. 2006. PMID: 16901483 Free article.
Involvement of sphingolipids in apoptin-induced cell killing.
Liu X, Zeidan YH, Elojeimy S, Holman DH, El-Zawahry AM, Guo GW, Bielawska A, Bielawski J, Szulc Z, Rubinchik S, Dong JY, Keane TE, Tavassoli M, Hannun YA, Norris JS. Liu X, et al. Mol Ther. 2006 Nov;14(5):627-36. doi: 10.1016/j.ymthe.2006.07.001. Epub 2006 Aug 22. Mol Ther. 2006. PMID: 16926120 Free article.
Role of acid ceramidase in resistance to FasL: therapeutic approaches based on acid ceramidase inhibitors and FasL gene therapy.
Elojeimy S, Liu X, McKillop JC, El-Zawahry AM, Holman DH, Cheng JY, Meacham WD, Mahdy AE, Saad AF, Turner LS, Cheng J, A Day T, Dong JY, Bielawska A, Hannun YA, Norris JS. Elojeimy S, et al. Among authors: liu x. Mol Ther. 2007 Jul;15(7):1259-63. doi: 10.1038/sj.mt.6300167. Epub 2007 Apr 10. Mol Ther. 2007. PMID: 17426710 Free article.
Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.
Holman DH, Turner LS, El-Zawahry A, Elojeimy S, Liu X, Bielawski J, Szulc ZM, Norris K, Zeidan YH, Hannun YA, Bielawska A, Norris JS. Holman DH, et al. Among authors: liu x. Cancer Chemother Pharmacol. 2008 Feb;61(2):231-42. doi: 10.1007/s00280-007-0465-0. Epub 2007 Apr 12. Cancer Chemother Pharmacol. 2008. PMID: 17429631
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