Chung AW - Search Results

1

Loss of elastic fiber integrity and reduction of vascular smooth muscle contraction resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in the thoracic aortic aneurysm in Marfan syndrome.

Chung AW, Au Yeung K, Sandor GG, Judge DP, Dietz HC, van Breemen C. Chung AW, et al. Circ Res. 2007 Aug 31;101(5):512-22. doi: 10.1161/CIRCRESAHA.107.157776. Epub 2007 Jul 19. Circ Res. 2007. PMID: 17641224

2

Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.

Chung AW, Au Yeung K, Cortes SF, Sandor GG, Judge DP, Dietz HC, van Breemen C. Chung AW, et al. Br J Pharmacol. 2007 Apr;150(8):1075-83. doi: 10.1038/sj.bjp.0707181. Epub 2007 Mar 5. Br J Pharmacol. 2007. PMID: 17339838 Free PMC article.

3

Imbalanced synthesis of cyclooxygenase-derived thromboxane A2 and prostacyclin compromises vasomotor function of the thoracic aorta in Marfan syndrome.

Chung AW, Yang HH, van Breemen C. Chung AW, et al. Br J Pharmacol. 2007 Oct;152(3):305-12. doi: 10.1038/sj.bjp.0707391. Epub 2007 Jul 16. Br J Pharmacol. 2007. PMID: 17641673 Free PMC article.

4

Dysfunction of endothelial and smooth muscle cells in small arteries of a mouse model of Marfan syndrome.

Syyong HT, Chung AW, Yang HH, van Breemen C. Syyong HT, et al. Among authors: chung aw. Br J Pharmacol. 2009 Nov;158(6):1597-608. doi: 10.1111/j.1476-5381.2009.00439.x. Epub 2009 Oct 8. Br J Pharmacol. 2009. PMID: 19814726 Free PMC article.

5

Marfan syndrome decreases Ca2+ wave frequency and vasoconstriction in murine mesenteric resistance arteries without changing underlying mechanisms.

Syyong HT, Chung AW, van Breemen C. Syyong HT, et al. Among authors: chung aw. J Vasc Res. 2011;48(2):150-62. doi: 10.1159/000318804. Epub 2010 Oct 8. J Vasc Res. 2011. PMID: 20926894 Free article.

6

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

Chung AW, Yang HH, Radomski MW, van Breemen C. Chung AW, et al. Circ Res. 2008 Apr 25;102(8):e73-85. doi: 10.1161/CIRCRESAHA.108.174367. Epub 2008 Apr 3. Circ Res. 2008. PMID: 18388324

7

Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome.

Yang HH, Kim JM, Chum E, van Breemen C, Chung AW. Yang HH, et al. Among authors: chung aw. Br J Pharmacol. 2009 Nov;158(6):1503-12. doi: 10.1111/j.1476-5381.2009.00443.x. Epub 2009 Oct 8. Br J Pharmacol. 2009. PMID: 19814725 Free PMC article.

8

Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress.

Yang HH, van Breemen C, Chung AW. Yang HH, et al. Among authors: chung aw. Vascul Pharmacol. 2010 Jan-Feb;52(1-2):37-45. doi: 10.1016/j.vph.2009.10.005. Epub 2009 Oct 29. Vascul Pharmacol. 2010. PMID: 19879959

9

Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome.

Yang HH, Kim JM, Chum E, van Breemen C, Chung AW. Yang HH, et al. Among authors: chung aw. J Thorac Cardiovasc Surg. 2010 Aug;140(2):305-312.e2. doi: 10.1016/j.jtcvs.2009.10.039. Epub 2010 Feb 26. J Thorac Cardiovasc Surg. 2010. PMID: 20189193 Free article.

10

Reduced expression of vascular endothelial growth factor paralleled with the increased angiostatin expression resulting from the upregulated activities of matrix metalloproteinase-2 and -9 in human type 2 diabetic arterial vasculature.

Chung AW, Hsiang YN, Matzke LA, McManus BM, van Breemen C, Okon EB. Chung AW, et al. Circ Res. 2006 Jul 21;99(2):140-8. doi: 10.1161/01.RES.0000232352.90786.fa. Epub 2006 Jun 15. Circ Res. 2006. PMID: 16778129

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