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LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.
Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, Tontonoz P. Hong C, et al. Among authors: tangirala rk. J Lipid Res. 2012 Jun;53(6):1126-33. doi: 10.1194/jlr.M022061. Epub 2012 Mar 26. J Lipid Res. 2012. PMID: 22454476 Free PMC article.
Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Tangirala RK, et al. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11896-901. doi: 10.1073/pnas.182199799. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193651 Free PMC article.
Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis.
Tarling EJ, Bojanic DD, Tangirala RK, Wang X, Lovgren-Sandblom A, Lusis AJ, Bjorkhem I, Edwards PA. Tarling EJ, et al. Among authors: tangirala rk. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1174-80. doi: 10.1161/ATVBAHA.110.205617. Epub 2010 Mar 18. Arterioscler Thromb Vasc Biol. 2010. PMID: 20299684 Free PMC article.
The LXR-Idol axis differentially regulates plasma LDL levels in primates and mice.
Hong C, Marshall SM, McDaniel AL, Graham M, Layne JD, Cai L, Scotti E, Boyadjian R, Kim J, Chamberlain BT, Tangirala RK, Jung ME, Fong L, Lee R, Young SG, Temel RE, Tontonoz P. Hong C, et al. Among authors: tangirala rk. Cell Metab. 2014 Nov 4;20(5):910-918. doi: 10.1016/j.cmet.2014.10.001. Epub 2014 Nov 4. Cell Metab. 2014. PMID: 25440061 Free PMC article.
44 results