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Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, Law RE, Collins JL, Willson TM, Tontonoz P. Joseph SB, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7604-9. doi: 10.1073/pnas.112059299. Proc Natl Acad Sci U S A. 2002. PMID: 12032330 Free PMC article.
Impaired development of atherosclerosis in Abcg1-/- Apoe-/- mice: identification of specific oxysterols that both accumulate in Abcg1-/- Apoe-/- tissues and induce apoptosis.
Tarling EJ, Bojanic DD, Tangirala RK, Wang X, Lovgren-Sandblom A, Lusis AJ, Bjorkhem I, Edwards PA. Tarling EJ, et al. Among authors: wang x. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1174-80. doi: 10.1161/ATVBAHA.110.205617. Epub 2010 Mar 18. Arterioscler Thromb Vasc Biol. 2010. PMID: 20299684 Free PMC article.
LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice.
Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, Tontonoz P. Hong C, et al. Among authors: wang x. J Lipid Res. 2012 Jun;53(6):1126-33. doi: 10.1194/jlr.M022061. Epub 2012 Mar 26. J Lipid Res. 2012. PMID: 22454476 Free PMC article.
Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Tangirala RK, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11896-901. doi: 10.1073/pnas.182199799. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193651 Free PMC article.
FXR deficiency causes reduced atherosclerosis in Ldlr-/- mice.
Zhang Y, Wang X, Vales C, Lee FY, Lee H, Lusis AJ, Edwards PA. Zhang Y, et al. Among authors: wang x. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2316-21. doi: 10.1161/01.ATV.0000235697.35431.05. Epub 2006 Jul 6. Arterioscler Thromb Vasc Biol. 2006. PMID: 16825595
207,114 results
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