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P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias.
Mooren JJ, Gültekin SE, Straetmans JM, Haesevoets A, Peutz-Kootstra CJ, Huebbers CU, Dienes HP, Wieland U, Ramaekers FC, Kremer B, Speel EJ, Klussmann JP. Mooren JJ, et al. Among authors: haesevoets a. Int J Cancer. 2014 May 1;134(9):2108-17. doi: 10.1002/ijc.28534. Epub 2013 Oct 21. Int J Cancer. 2014. PMID: 24127203
Human papillomavirus multiplex ligation-dependent probe amplification assay for the assessment of viral load, integration, and gain of telomerase-related genes in cervical malignancies.
Theelen W, Litjens RJ, Vinokurova S, Haesevoets A, Reijans M, Simons G, Smedts F, Herrington CS, Ramaekers FC, von Knebel Doeberitz M, Speel EJ, Hopman AH. Theelen W, et al. Among authors: haesevoets a. Hum Pathol. 2013 Nov;44(11):2410-8. doi: 10.1016/j.humpath.2013.04.026. Epub 2013 Aug 19. Hum Pathol. 2013. PMID: 23968641 Free article.
Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.
Olthof NC, Speel EJ, Kolligs J, Haesevoets A, Henfling M, Ramaekers FC, Preuss SF, Drebber U, Wieland U, Silling S, Lam WL, Vucic EA, Kremer B, Klussmann JP, Huebbers CU. Olthof NC, et al. Among authors: haesevoets a. PLoS One. 2014 Feb 24;9(2):e88718. doi: 10.1371/journal.pone.0088718. eCollection 2014. PLoS One. 2014. PMID: 24586376 Free PMC article.
CD44 and OTP are strong prognostic markers for pulmonary carcinoids.
Swarts DR, Henfling ME, Van Neste L, van Suylen RJ, Dingemans AM, Dinjens WN, Haesevoets A, Rudelius M, Thunnissen E, Volante M, Van Criekinge W, van Engeland M, Ramaekers FC, Speel EJ. Swarts DR, et al. Among authors: haesevoets a. Clin Cancer Res. 2013 Apr 15;19(8):2197-207. doi: 10.1158/1078-0432.CCR-12-3078. Epub 2013 Feb 26. Clin Cancer Res. 2013. PMID: 23444222 Free article.
Chromosome instability predicts progression of premalignant lesions of the larynx.
Bergshoeff VE, Van der Heijden SJ, Haesevoets A, Litjens SG, Bot FJ, Voogd AC, Chenault MN, Hopman AH, Schuuring E, Van der Wal JM, Manni JJ, Ramaekers FC, Kremer B, Speel EJ. Bergshoeff VE, et al. Among authors: haesevoets a. Pathology. 2014 Apr;46(3):216-24. doi: 10.1097/PAT.0000000000000068. Pathology. 2014. PMID: 24614717
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