Guo T - Search Results

1

Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor.

Guo T, Agaram NP, Wong GC, Hom G, D'Adamo D, Maki RG, Schwartz GK, Veach D, Clarkson BD, Singer S, DeMatteo RP, Besmer P, Antonescu CR. Guo T, et al. Clin Cancer Res. 2007 Aug 15;13(16):4874-81. doi: 10.1158/1078-0432.CCR-07-0484. Clin Cancer Res. 2007. PMID: 17699867

2

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation.

Antonescu CR, Besmer P, Guo T, Arkun K, Hom G, Koryotowski B, Leversha MA, Jeffrey PD, Desantis D, Singer S, Brennan MF, Maki RG, DeMatteo RP. Antonescu CR, et al. Among authors: guo t. Clin Cancer Res. 2005 Jun 1;11(11):4182-90. doi: 10.1158/1078-0432.CCR-04-2245. Clin Cancer Res. 2005. PMID: 15930355

3

Pathologic and molecular heterogeneity in imatinib-stable or imatinib-responsive gastrointestinal stromal tumors.

Agaram NP, Besmer P, Wong GC, Guo T, Socci ND, Maki RG, DeSantis D, Brennan MF, Singer S, DeMatteo RP, Antonescu CR. Agaram NP, et al. Among authors: guo t. Clin Cancer Res. 2007 Jan 1;13(1):170-81. doi: 10.1158/1078-0432.CCR-06-1508. Clin Cancer Res. 2007. PMID: 17200352 Free article.

4

L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition.

Antonescu CR, Busam KJ, Francone TD, Wong GC, Guo T, Agaram NP, Besmer P, Jungbluth A, Gimbel M, Chen CT, Veach D, Clarkson BD, Paty PB, Weiser MR. Antonescu CR, et al. Among authors: guo t. Int J Cancer. 2007 Jul 15;121(2):257-64. doi: 10.1002/ijc.22681. Int J Cancer. 2007. PMID: 17372901

5

Molecular characterization of pediatric gastrointestinal stromal tumors.

Agaram NP, Laquaglia MP, Ustun B, Guo T, Wong GC, Socci ND, Maki RG, DeMatteo RP, Besmer P, Antonescu CR. Agaram NP, et al. Among authors: guo t. Clin Cancer Res. 2008 May 15;14(10):3204-15. doi: 10.1158/1078-0432.CCR-07-1984. Clin Cancer Res. 2008. PMID: 18483389 Free PMC article.

6

Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors.

Agaram NP, Wong GC, Guo T, Maki RG, Singer S, Dematteo RP, Besmer P, Antonescu CR. Agaram NP, et al. Among authors: guo t. Genes Chromosomes Cancer. 2008 Oct;47(10):853-9. doi: 10.1002/gcc.20589. Genes Chromosomes Cancer. 2008. PMID: 18615679 Free PMC article.

7

Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KITAY502-3ins mutation: an in vitro mutagenesis screen for drug resistance.

Guo T, Hajdu M, Agaram NP, Shinoda H, Veach D, Clarkson BD, Maki RG, Singer S, Dematteo RP, Besmer P, Antonescu CR. Guo T, et al. Clin Cancer Res. 2009 Nov 15;15(22):6862-70. doi: 10.1158/1078-0432.CCR-09-1315. Epub 2009 Oct 27. Clin Cancer Res. 2009. PMID: 19861442 Free PMC article.

8

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.

Balachandran VP, Cavnar MJ, Zeng S, Bamboat ZM, Ocuin LM, Obaid H, Sorenson EC, Popow R, Ariyan C, Rossi F, Besmer P, Guo T, Antonescu CR, Taguchi T, Yuan J, Wolchok JD, Allison JP, DeMatteo RP. Balachandran VP, et al. Among authors: guo t. Nat Med. 2011 Aug 28;17(9):1094-100. doi: 10.1038/nm.2438. Nat Med. 2011. PMID: 21873989 Free PMC article.

9

Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions.

Guo T, Zhang L, Chang NE, Singer S, Maki RG, Antonescu CR. Guo T, et al. Genes Chromosomes Cancer. 2011 Jan;50(1):25-33. doi: 10.1002/gcc.20827. Genes Chromosomes Cancer. 2011. PMID: 20949568 Free PMC article.

10

CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers.

Chen J, Guo T, Zhang L, Qin LX, Singer S, Maki RG, Taguchi T, Dematteo R, Besmer P, Antonescu CR. Chen J, et al. Among authors: guo t. Genes Chromosomes Cancer. 2012 Feb;51(2):186-95. doi: 10.1002/gcc.20942. Epub 2011 Nov 10. Genes Chromosomes Cancer. 2012. PMID: 22076958 Free PMC article.

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