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An innovative LC-MS/MS-based method for determining CYP 17 and CYP 19 activity in the adipose tissue of pre- and postmenopausal and ovariectomized women using 13C-labeled steroid substrates.
Kinoshita T, Honma S, Shibata Y, Yamashita K, Watanabe Y, Maekubo H, Okuyama M, Takashima A, Takeshita N. Kinoshita T, et al. Among authors: okuyama m. J Clin Endocrinol Metab. 2014 Apr;99(4):1339-47. doi: 10.1210/jc.2013-3715. Epub 2014 Jan 23. J Clin Endocrinol Metab. 2014. PMID: 24456285
Measurement of peripheral plasma 18-oxocortisol can discriminate unilateral adenoma from bilateral diseases in patients with primary aldosteronism.
Satoh F, Morimoto R, Ono Y, Iwakura Y, Omata K, Kudo M, Takase K, Seiji K, Sasamoto H, Honma S, Okuyama M, Yamashita K, Gomez-Sanchez CE, Rainey WE, Arai Y, Sasano H, Nakamura Y, Ito S. Satoh F, et al. Among authors: okuyama m. Hypertension. 2015 May;65(5):1096-102. doi: 10.1161/HYPERTENSIONAHA.114.04453. Epub 2015 Mar 16. Hypertension. 2015. PMID: 25776074 Free PMC article.
In vitro method for assessing hepatic drug metabolism.
Okuyama M, Inoue C, Aijima K, Nakamura Y, Kaburagi T, Shigematsu A. Okuyama M, et al. Biol Pharm Bull. 1997 Jan;20(1):1-5. doi: 10.1248/bpb.20.1. Biol Pharm Bull. 1997. PMID: 9013796 Free article.
532 results