Austin CP - Search Results

1

Differentiating Alzheimer disease-associated aggregates with small molecules.

Honson NS, Johnson RL, Huang W, Inglese J, Austin CP, Kuret J. Honson NS, et al. Among authors: austin cp. Neurobiol Dis. 2007 Dec;28(3):251-60. doi: 10.1016/j.nbd.2007.07.018. Epub 2007 Jul 28. Neurobiol Dis. 2007. PMID: 17761424 Free PMC article.

2

Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening.

Crowe A, Huang W, Ballatore C, Johnson RL, Hogan AM, Huang R, Wichterman J, McCoy J, Huryn D, Auld DS, Smith AB 3rd, Inglese J, Trojanowski JQ, Austin CP, Brunden KR, Lee VM. Crowe A, et al. Among authors: austin cp. Biochemistry. 2009 Aug 18;48(32):7732-45. doi: 10.1021/bi9006435. Biochemistry. 2009. PMID: 19580328 Free PMC article.

3

A quantitative high-throughput screen identifies potential epigenetic modulators of gene expression.

Johnson RL, Huang W, Jadhav A, Austin CP, Inglese J, Martinez ED. Johnson RL, et al. Among authors: austin cp. Anal Biochem. 2008 Apr 15;375(2):237-48. doi: 10.1016/j.ab.2007.12.028. Epub 2007 Dec 25. Anal Biochem. 2008. PMID: 18211814 Free PMC article.

4

N4-phenyl modifications of N2-(2-hydroxyl)ethyl-6-(pyrrolidin-1-yl)-1,3,5-triazine-2,4-diamines enhance glucocerebrosidase inhibition by small molecules with potential as chemical chaperones for Gaucher disease.

Huang W, Zheng W, Urban DJ, Inglese J, Sidransky E, Austin CP, Thomas CJ. Huang W, et al. Among authors: austin cp. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5783-9. doi: 10.1016/j.bmcl.2007.08.050. Epub 2007 Aug 28. Bioorg Med Chem Lett. 2007. PMID: 17827006 Free PMC article.

5

Identification of Potent and Selective Diphenylpropanamide RORγ Inhibitors.

Huh JR, Englund EE, Wang H, Huang R, Huang P, Rastinejad F, Inglese J, Austin CP, Johnson RL, Huang W, Littman DR. Huh JR, et al. Among authors: austin cp. ACS Med Chem Lett. 2013 Jan 10;4(1):79-84. doi: 10.1021/ml300286h. ACS Med Chem Lett. 2013. PMID: 24040486 Free PMC article.

6

A quantitative high-throughput screen for modulators of IL-6 signaling: a model for interrogating biological networks using chemical libraries.

Johnson RL, Huang R, Jadhav A, Southall N, Wichterman J, MacArthur R, Xia M, Bi K, Printen J, Austin CP, Inglese J. Johnson RL, et al. Among authors: austin cp. Mol Biosyst. 2009 Sep;5(9):1039-50. doi: 10.1039/b902021g. Epub 2009 Jun 19. Mol Biosyst. 2009. PMID: 19668870 Free PMC article.

7

Identification of small molecule modulators of gene transcription with anticancer activity.

Tran TA, Wichterman-Kouznetsova J, Varghese D, Huang R, Huang W, Becker M, Austin CP, Inglese J, Johnson RL, Martinez ED. Tran TA, et al. Among authors: austin cp. ACS Chem Biol. 2014 Nov 21;9(11):2603-11. doi: 10.1021/cb500532x. Epub 2014 Sep 16. ACS Chem Biol. 2014. PMID: 25188650 Free PMC article.

8

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Inglese J, Auld DS, Jadhav A, Johnson RL, Simeonov A, Yasgar A, Zheng W, Austin CP. Inglese J, et al. Among authors: austin cp. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11473-8. doi: 10.1073/pnas.0604348103. Epub 2006 Jul 24. Proc Natl Acad Sci U S A. 2006. PMID: 16864780 Free PMC article.

9

High-throughput screening assays for the identification of chemical probes.

Inglese J, Johnson RL, Simeonov A, Xia M, Zheng W, Austin CP, Auld DS. Inglese J, et al. Among authors: austin cp. Nat Chem Biol. 2007 Aug;3(8):466-79. doi: 10.1038/nchembio.2007.17. Nat Chem Biol. 2007. PMID: 17637779 Review.

10

Identification of oxadiazoles as new drug leads for the control of schistosomiasis.

Sayed AA, Simeonov A, Thomas CJ, Inglese J, Austin CP, Williams DL. Sayed AA, et al. Among authors: austin cp. Nat Med. 2008 Apr;14(4):407-12. doi: 10.1038/nm1737. Epub 2008 Mar 16. Nat Med. 2008. PMID: 18345010 Free PMC article.

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