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PET-CT imaging with [(18)F]-gefitinib to measure Abcb1a/1b (P-gp) and Abcg2 (Bcrp1) mediated drug-drug interactions at the murine blood-brain barrier.
Vlaming ML, Läppchen T, Jansen HT, Kivits S, van Driel A, van de Steeg E, van der Hoorn JW, Sio CF, Steinbach OC, DeGroot J. Vlaming ML, et al. Among authors: van de steeg e, van der hoorn jw, van driel a. Nucl Med Biol. 2015 Nov;42(11):833-41. doi: 10.1016/j.nucmedbio.2015.07.004. Epub 2015 Jul 15. Nucl Med Biol. 2015. PMID: 26264927
Feasibility of SPECT-CT Imaging to Study the Pharmacokinetics of Antisense Oligonucleotides in a Mouse Model of Duchenne Muscular Dystrophy.
van de Steeg E, Läppchen T, Aguilera B, Jansen HT, Muilwijk D, Vermue R, van der Hoorn JW, Donato K, Rossin R, de Visser PC, Vlaming MLH. van de Steeg E, et al. Among authors: van der hoorn jw. Nucleic Acid Ther. 2017 Aug;27(4):221-231. doi: 10.1089/nat.2016.0649. Epub 2017 Apr 18. Nucleic Acid Ther. 2017. PMID: 28418733
Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.
Simic B, Mocharla P, Crucet M, Osto E, Kratzer A, Stivala S, Kühnast S, Speer T, Doycheva P, Princen HM, van der Hoorn JW, Jukema JW, Giral H, Tailleux A, Landmesser U, Staels B, Lüscher TF. Simic B, et al. Among authors: van der hoorn jw. Atherosclerosis. 2017 Feb;257:186-194. doi: 10.1016/j.atherosclerosis.2017.01.011. Epub 2017 Jan 16. Atherosclerosis. 2017. PMID: 28152406
Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin.
de Haan W, de Vries-van der Weij J, van der Hoorn JW, Gautier T, van der Hoogt CC, Westerterp M, Romijn JA, Jukema JW, Havekes LM, Princen HM, Rensen PC. de Haan W, et al. Among authors: van der hoogt cc, van der hoorn jw. Circulation. 2008 May 13;117(19):2515-22. doi: 10.1161/CIRCULATIONAHA.107.761965. Epub 2008 May 5. Circulation. 2008. PMID: 18458167
38 results