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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.
Park JH, Adoro S, Guinter T, Erman B, Alag AS, Catalfamo M, Kimura MY, Cui Y, Lucas PJ, Gress RE, Kubo M, Hennighausen L, Feigenbaum L, Singer A. Park JH, et al. Among authors: adoro s. Nat Immunol. 2010 Mar;11(3):257-64. doi: 10.1038/ni.1840. Epub 2010 Jan 31. Nat Immunol. 2010. PMID: 20118929 Free PMC article.
Coreceptor gene imprinting governs thymocyte lineage fate.
Adoro S, McCaughtry T, Erman B, Alag A, Van Laethem F, Park JH, Tai X, Kimura M, Wang L, Grinberg A, Kubo M, Bosselut R, Love P, Singer A. Adoro S, et al. EMBO J. 2012 Jan 18;31(2):366-77. doi: 10.1038/emboj.2011.388. Epub 2011 Oct 28. EMBO J. 2012. PMID: 22036949 Free PMC article.
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway.
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH. Chen X, et al. Among authors: adoro s. Nature. 2014 Apr 3;508(7494):103-107. doi: 10.1038/nature13119. Epub 2014 Mar 23. Nature. 2014. PMID: 24670641 Free PMC article.
23 results