Feigenbaum L - Search Results

1

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A. Park JH, et al. Among authors: feigenbaum l. Nat Immunol. 2007 Oct;8(10):1049-59. doi: 10.1038/ni1512. Epub 2007 Sep 16. Nat Immunol. 2007. PMID: 17873878

2

Early TCRalpha expression generates TCRalphagamma complexes that signal the DN-to-DP transition and impair development.

Erman B, Feigenbaum L, Coligan JE, Singer A. Erman B, et al. Among authors: feigenbaum l. Nat Immunol. 2002 Jun;3(6):564-9. doi: 10.1038/ni800. Epub 2002 May 20. Nat Immunol. 2002. PMID: 12021779

3

CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain.

Bhandoola A, Bosselut R, Yu Q, Cowan ML, Feigenbaum L, Love PE, Singer A. Bhandoola A, et al. Among authors: feigenbaum l. Eur J Immunol. 2002 Jun;32(6):1811-7. doi: 10.1002/1521-4141(200206)32:6<1811::AID-IMMU1811>3.0.CO;2-G. Eur J Immunol. 2002. PMID: 12115665 Free article.

4

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

Yu Q, Erman B, Park JH, Feigenbaum L, Singer A. Yu Q, et al. Among authors: feigenbaum l. J Exp Med. 2004 Sep 20;200(6):797-803. doi: 10.1084/jem.20032183. Epub 2004 Sep 13. J Exp Med. 2004. PMID: 15365098 Free PMC article.

5

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

Tai X, Cowan M, Feigenbaum L, Singer A. Tai X, et al. Among authors: feigenbaum l. Nat Immunol. 2005 Feb;6(2):152-62. doi: 10.1038/ni1160. Epub 2005 Jan 9. Nat Immunol. 2005. PMID: 15640801

6

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection.

Sun G, Liu X, Mercado P, Jenkinson SR, Kypriotou M, Feigenbaum L, Galéra P, Bosselut R. Sun G, et al. Among authors: feigenbaum l. Nat Immunol. 2005 Apr;6(4):373-81. doi: 10.1038/ni1183. Epub 2005 Mar 6. Nat Immunol. 2005. PMID: 15750595

7

Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

Sarafova SD, Erman B, Yu Q, Van Laethem F, Guinter T, Sharrow SO, Feigenbaum L, Wildt KF, Ellmeier W, Singer A. Sarafova SD, et al. Among authors: feigenbaum l. Immunity. 2005 Jul;23(1):75-87. doi: 10.1016/j.immuni.2005.05.011. Immunity. 2005. PMID: 16039581 Free article.

8

Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection.

Yu Q, Park JH, Doan LL, Erman B, Feigenbaum L, Singer A. Yu Q, et al. Among authors: feigenbaum l. J Exp Med. 2006 Jan 23;203(1):165-75. doi: 10.1084/jem.20051836. Epub 2006 Jan 3. J Exp Med. 2006. PMID: 16390939 Free PMC article.

9

Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic.

Adoro S, Erman B, Sarafova SD, Van Laethem F, Park JH, Feigenbaum L, Singer A. Adoro S, et al. Among authors: feigenbaum l. J Immunol. 2008 Nov 15;181(10):6975-83. doi: 10.4049/jimmunol.181.10.6975. J Immunol. 2008. PMID: 18981117 Free PMC article.

10

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

Park JH, Adoro S, Guinter T, Erman B, Alag AS, Catalfamo M, Kimura MY, Cui Y, Lucas PJ, Gress RE, Kubo M, Hennighausen L, Feigenbaum L, Singer A. Park JH, et al. Among authors: feigenbaum l. Nat Immunol. 2010 Mar;11(3):257-64. doi: 10.1038/ni.1840. Epub 2010 Jan 31. Nat Immunol. 2010. PMID: 20118929 Free PMC article.

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