Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic.
Nakanaga K, Ogura Y, Toyoda A, Yoshida M, Fukano H, Fujiwara N, Miyamoto Y, Nakata N, Kazumi Y, Maeda S, Ooka T, Goto M, Tanigawa K, Mitarai S, Suzuki K, Ishii N, Ato M, Hayashi T, Hoshino Y.
Nakanaga K, et al. Among authors: goto m.
Sci Rep. 2018 May 29;8(1):8218. doi: 10.1038/s41598-018-26425-1.
Sci Rep. 2018.
PMID: 29844323
Free PMC article.