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643 results

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Page 1
Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway.
John M, Constien R, Akinc A, Goldberg M, Moon YA, Spranger M, Hadwiger P, Soutschek J, Vornlocher HP, Manoharan M, Stoffel M, Langer R, Anderson DG, Horton JD, Koteliansky V, Bumcrot D. John M, et al. Among authors: stoffel m. Nature. 2007 Oct 11;449(7163):745-7. doi: 10.1038/nature06179. Epub 2007 Sep 26. Nature. 2007. PMID: 17898712 Free PMC article.
A pancreatic islet-specific microRNA regulates insulin secretion.
Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M. Poy MN, et al. Among authors: stoffel m. Nature. 2004 Nov 11;432(7014):226-30. doi: 10.1038/nature03076. Nature. 2004. PMID: 15538371
Combinatorial microRNA target predictions.
Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N. Krek A, et al. Among authors: stoffel m. Nat Genet. 2005 May;37(5):495-500. doi: 10.1038/ng1536. Epub 2005 Apr 3. Nat Genet. 2005. PMID: 15806104
Silencing of microRNAs in vivo with 'antagomirs'.
Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. Krützfeldt J, et al. Among authors: stoffel m. Nature. 2005 Dec 1;438(7068):685-9. doi: 10.1038/nature04303. Epub 2005 Oct 30. Nature. 2005. PMID: 16258535
Specificity, duplex degradation and subcellular localization of antagomirs.
Krützfeldt J, Kuwajima S, Braich R, Rajeev KG, Pena J, Tuschl T, Manoharan M, Stoffel M. Krützfeldt J, et al. Among authors: stoffel m. Nucleic Acids Res. 2007;35(9):2885-92. doi: 10.1093/nar/gkm024. Epub 2007 Apr 16. Nucleic Acids Res. 2007. PMID: 17439965 Free PMC article.
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.
Wolfrum C, Shi S, Jayaprakash KN, Jayaraman M, Wang G, Pandey RK, Rajeev KG, Nakayama T, Charrise K, Ndungo EM, Zimmermann T, Koteliansky V, Manoharan M, Stoffel M. Wolfrum C, et al. Among authors: stoffel m. Nat Biotechnol. 2007 Oct;25(10):1149-57. doi: 10.1038/nbt1339. Epub 2007 Sep 16. Nat Biotechnol. 2007. PMID: 17873866
MicroRNAs 103 and 107 regulate insulin sensitivity.
Trajkovski M, Hausser J, Soutschek J, Bhat B, Akin A, Zavolan M, Heim MH, Stoffel M. Trajkovski M, et al. Among authors: stoffel m. Nature. 2011 Jun 8;474(7353):649-53. doi: 10.1038/nature10112. Nature. 2011. PMID: 21654750
Harnessing a physiologic mechanism for siRNA delivery with mimetic lipoprotein particles.
Nakayama T, Butler JS, Sehgal A, Severgnini M, Racie T, Sharman J, Ding F, Morskaya SS, Brodsky J, Tchangov L, Kosovrasti V, Meys M, Nechev L, Wang G, Peng CG, Fang Y, Maier M, Rajeev KG, Li R, Hettinger J, Barros S, Clausen V, Zhang X, Wang Q, Hutabarat R, Dokholyan NV, Wolfrum C, Manoharan M, Kotelianski V, Stoffel M, Sah DW. Nakayama T, et al. Among authors: stoffel m. Mol Ther. 2012 Aug;20(8):1582-9. doi: 10.1038/mt.2012.33. Epub 2012 Jun 5. Mol Ther. 2012. PMID: 22850721 Free PMC article.
643 results