Birnbaum MJ - Search Results

1

A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. O'Neill BT, et al. Among authors: birnbaum mj. Cell Metab. 2007 Oct;6(4):294-306. doi: 10.1016/j.cmet.2007.09.001. Cell Metab. 2007. PMID: 17908558 Free PMC article.

2

Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.

Symons JD, McMillin SL, Riehle C, Tanner J, Palionyte M, Hillas E, Jones D, Cooksey RC, Birnbaum MJ, McClain DA, Zhang QJ, Gale D, Wilson LJ, Abel ED. Symons JD, et al. Among authors: birnbaum mj. Circ Res. 2009 May 8;104(9):1085-94. doi: 10.1161/CIRCRESAHA.108.189316. Epub 2009 Apr 2. Circ Res. 2009. PMID: 19342603 Free PMC article.

3

Akt2 is required for hepatic lipid accumulation in models of insulin resistance.

Leavens KF, Easton RM, Shulman GI, Previs SF, Birnbaum MJ. Leavens KF, et al. Among authors: birnbaum mj. Cell Metab. 2009 Nov;10(5):405-18. doi: 10.1016/j.cmet.2009.10.004. Cell Metab. 2009. PMID: 19883618 Free PMC article.

4

Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.

Wan M, Leavens KF, Saleh D, Easton RM, Guertin DA, Peterson TR, Kaestner KH, Sabatini DM, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Cell Metab. 2011 Oct 5;14(4):516-27. doi: 10.1016/j.cmet.2011.09.001. Cell Metab. 2011. PMID: 21982711 Free PMC article.

5

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Boxer RB, et al. Among authors: birnbaum mj. Cell Metab. 2006 Dec;4(6):475-90. doi: 10.1016/j.cmet.2006.10.011. Cell Metab. 2006. PMID: 17141631 Free article.

6

Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production.

Titchenell PM, Quinn WJ, Lu M, Chu Q, Lu W, Li C, Chen H, Monks BR, Chen J, Rabinowitz JD, Birnbaum MJ. Titchenell PM, et al. Among authors: birnbaum mj. Cell Metab. 2016 Jun 14;23(6):1154-1166. doi: 10.1016/j.cmet.2016.04.022. Epub 2016 May 26. Cell Metab. 2016. PMID: 27238637 Free PMC article.

7

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance.

Holland WL, Brozinick JT, Wang LP, Hawkins ED, Sargent KM, Liu Y, Narra K, Hoehn KL, Knotts TA, Siesky A, Nelson DH, Karathanasis SK, Fontenot GK, Birnbaum MJ, Summers SA. Holland WL, et al. Among authors: birnbaum mj. Cell Metab. 2007 Mar;5(3):167-79. doi: 10.1016/j.cmet.2007.01.002. Cell Metab. 2007. PMID: 17339025 Free article.

8

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.

Wan M, Leavens KF, Hunter RW, Koren S, von Wilamowitz-Moellendorff A, Lu M, Satapati S, Chu Q, Sakamoto K, Burgess SC, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Cell Metab. 2013 Jul 2;18(1):99-105. doi: 10.1016/j.cmet.2013.06.001. Cell Metab. 2013. PMID: 23823480 Free PMC article.

9

Insulin regulates adipocyte lipolysis via an Akt-independent signaling pathway.

Choi SM, Tucker DF, Gross DN, Easton RM, DiPilato LM, Dean AS, Monks BR, Birnbaum MJ. Choi SM, et al. Among authors: birnbaum mj. Mol Cell Biol. 2010 Nov;30(21):5009-20. doi: 10.1128/MCB.00797-10. Epub 2010 Aug 23. Mol Cell Biol. 2010. PMID: 20733001 Free PMC article.

10

Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms.

Wang Q, Yu WN, Chen X, Peng XD, Jeon SM, Birnbaum MJ, Guzman G, Hay N. Wang Q, et al. Among authors: birnbaum mj. Cancer Cell. 2016 Apr 11;29(4):523-535. doi: 10.1016/j.ccell.2016.02.008. Epub 2016 Mar 17. Cancer Cell. 2016. PMID: 26996309 Free PMC article.

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